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A5EG87

- TYPH_BRASB

UniProt

A5EG87 - TYPH_BRASB

Protein

Putative thymidine phosphorylase

Gene

BBta_3062

Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 2 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

    GO - Molecular functioni

    1. phosphorylase activity Source: InterPro
    2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pyrimidine nucleobase metabolic process Source: InterPro
    2. pyrimidine nucleoside metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciBSP288000:GJBR-2911-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
    Alternative name(s):
    TdRPaseUniRule annotation
    Gene namesi
    Ordered Locus Names:BBta_3062
    OrganismiBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
    Taxonomic identifieri288000 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
    ProteomesiUP000000246: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 511511Putative thymidine phosphorylasePRO_0000314697Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi288000.BBta_3062.

    Structurei

    3D structure databases

    ProteinModelPortaliA5EG87.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0213.
    HOGENOMiHOG000252767.
    KOiK00758.
    OrthoDBiEOG61ZTGG.

    Family and domain databases

    Gene3Di3.40.1030.10. 1 hit.
    3.90.1170.30. 1 hit.
    HAMAPiMF_00703. Thymid_phosp_2.
    InterProiIPR000312. Glycosyl_Trfase_fam3.
    IPR017459. Glycosyl_Trfase_fam3_N_dom.
    IPR013102. PYNP_C.
    IPR000053. Pyrmidine_PPase.
    IPR017872. Pyrmidine_PPase_CS.
    IPR028579. Thym_Pase_Put.
    IPR013466. Thymidine/AMP_Pase.
    [Graphical view]
    PANTHERiPTHR10515. PTHR10515. 1 hit.
    PfamiPF02885. Glycos_trans_3N. 1 hit.
    PF00591. Glycos_transf_3. 1 hit.
    PF07831. PYNP_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000478. TP_PyNP. 1 hit.
    SMARTiSM00941. PYNP_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF47648. SSF47648. 1 hit.
    SSF52418. SSF52418. 1 hit.
    SSF54680. SSF54680. 1 hit.
    TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
    PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5EG87-1 [UniParc]FASTAAdd to Basket

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    MSTIDSARPQ LKIRSVALDT GRENVVVISR RSRALRPEVF SGFSRVELRC    50
    NSRTLLATLL ITDDDALVGP DEIGLSQPAL RRFAEPAGTF ATVSPATPPD 100
    SLEAVRAKIR GETLSDQAIS AVIDDLAHYR YSDMEIAAFL IGSASFMTSG 150
    ELLALTRAMA NAGTQLKWPE PVVVDKHCIG GIPGNRTSMV VVPIVAAHGL 200
    TIPKTSSRAI TSPAGTADTM EVLARVNVGA EEMKSIVAAC NGCVIWGGHV 250
    NLSPADDILI SVERPLSLDT REQMVASILS KKLAAGSTHL LLDLPVGPTA 300
    KLSSGAEAMR LRKLFEFVGD RFGLNVEVIT TDGRQPIGNG IGPVLEARDV 350
    MAVLGNEPGA PADLREKSLR LAAHLLEYDP KLRGGAGYQR ARELLDSGAA 400
    LKQMQKIIDA QGPTTSRNEL GDLAFDVKAG RDGIVSAIDC LRLNRLARTA 450
    GAPINKGAGI RLFKKIGDRV DQGEPLYRVF TCDPSEHDLA VAAAAADHGY 500
    GFADEPNGHQ R 511
    Length:511
    Mass (Da):54,383
    Last modified:January 15, 2008 - v2
    Checksum:i02CE1A5A2442C6FD
    GO

    Sequence cautioni

    The sequence ABQ35181.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000494 Genomic DNA. Translation: ABQ35181.1. Different initiation.
    RefSeqiWP_012043201.1. NC_009485.1.
    YP_001239087.1. NC_009485.1.

    Genome annotation databases

    EnsemblBacteriaiABQ35181; ABQ35181; BBta_3062.
    GeneIDi5149443.
    KEGGibbt:BBta_3062.
    PATRICi21206947. VBIBraSp29847_3156.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000494 Genomic DNA. Translation: ABQ35181.1 . Different initiation.
    RefSeqi WP_012043201.1. NC_009485.1.
    YP_001239087.1. NC_009485.1.

    3D structure databases

    ProteinModelPortali A5EG87.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 288000.BBta_3062.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ35181 ; ABQ35181 ; BBta_3062 .
    GeneIDi 5149443.
    KEGGi bbt:BBta_3062.
    PATRICi 21206947. VBIBraSp29847_3156.

    Phylogenomic databases

    eggNOGi COG0213.
    HOGENOMi HOG000252767.
    KOi K00758.
    OrthoDBi EOG61ZTGG.

    Enzyme and pathway databases

    BioCyci BSP288000:GJBR-2911-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1030.10. 1 hit.
    3.90.1170.30. 1 hit.
    HAMAPi MF_00703. Thymid_phosp_2.
    InterProi IPR000312. Glycosyl_Trfase_fam3.
    IPR017459. Glycosyl_Trfase_fam3_N_dom.
    IPR013102. PYNP_C.
    IPR000053. Pyrmidine_PPase.
    IPR017872. Pyrmidine_PPase_CS.
    IPR028579. Thym_Pase_Put.
    IPR013466. Thymidine/AMP_Pase.
    [Graphical view ]
    PANTHERi PTHR10515. PTHR10515. 1 hit.
    Pfami PF02885. Glycos_trans_3N. 1 hit.
    PF00591. Glycos_transf_3. 1 hit.
    PF07831. PYNP_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000478. TP_PyNP. 1 hit.
    SMARTi SM00941. PYNP_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47648. SSF47648. 1 hit.
    SSF52418. SSF52418. 1 hit.
    SSF54680. SSF54680. 1 hit.
    TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
    PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BTAi1 / ATCC BAA-1182.

    Entry informationi

    Entry nameiTYPH_BRASB
    AccessioniPrimary (citable) accession number: A5EG87
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3