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A5EG87

- TYPH_BRASB

UniProt

A5EG87 - TYPH_BRASB

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Protein
Putative thymidine phosphorylase
Gene
BBta_3062
Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciBSP288000:GJBR-2911-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase (EC:2.4.2.4)
Alternative name(s):
TdRPase
Gene namesi
Ordered Locus Names:BBta_3062
OrganismiBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Taxonomic identifieri288000 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000000246: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511Putative thymidine phosphorylaseUniRule annotation
PRO_0000314697Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi288000.BBta_3062.

Structurei

3D structure databases

ProteinModelPortaliA5EG87.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5EG87-1 [UniParc]FASTAAdd to Basket

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MSTIDSARPQ LKIRSVALDT GRENVVVISR RSRALRPEVF SGFSRVELRC    50
NSRTLLATLL ITDDDALVGP DEIGLSQPAL RRFAEPAGTF ATVSPATPPD 100
SLEAVRAKIR GETLSDQAIS AVIDDLAHYR YSDMEIAAFL IGSASFMTSG 150
ELLALTRAMA NAGTQLKWPE PVVVDKHCIG GIPGNRTSMV VVPIVAAHGL 200
TIPKTSSRAI TSPAGTADTM EVLARVNVGA EEMKSIVAAC NGCVIWGGHV 250
NLSPADDILI SVERPLSLDT REQMVASILS KKLAAGSTHL LLDLPVGPTA 300
KLSSGAEAMR LRKLFEFVGD RFGLNVEVIT TDGRQPIGNG IGPVLEARDV 350
MAVLGNEPGA PADLREKSLR LAAHLLEYDP KLRGGAGYQR ARELLDSGAA 400
LKQMQKIIDA QGPTTSRNEL GDLAFDVKAG RDGIVSAIDC LRLNRLARTA 450
GAPINKGAGI RLFKKIGDRV DQGEPLYRVF TCDPSEHDLA VAAAAADHGY 500
GFADEPNGHQ R 511
Length:511
Mass (Da):54,383
Last modified:January 15, 2008 - v2
Checksum:i02CE1A5A2442C6FD
GO

Sequence cautioni

The sequence ABQ35181.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000494 Genomic DNA. Translation: ABQ35181.1. Different initiation.
RefSeqiWP_012043201.1. NC_009485.1.
YP_001239087.1. NC_009485.1.

Genome annotation databases

EnsemblBacteriaiABQ35181; ABQ35181; BBta_3062.
GeneIDi5149443.
KEGGibbt:BBta_3062.
PATRICi21206947. VBIBraSp29847_3156.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000494 Genomic DNA. Translation: ABQ35181.1 . Different initiation.
RefSeqi WP_012043201.1. NC_009485.1.
YP_001239087.1. NC_009485.1.

3D structure databases

ProteinModelPortali A5EG87.
ModBasei Search...

Protein-protein interaction databases

STRINGi 288000.BBta_3062.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ35181 ; ABQ35181 ; BBta_3062 .
GeneIDi 5149443.
KEGGi bbt:BBta_3062.
PATRICi 21206947. VBIBraSp29847_3156.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci BSP288000:GJBR-2911-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BTAi1 / ATCC BAA-1182.

Entry informationi

Entry nameiTYPH_BRASB
AccessioniPrimary (citable) accession number: A5EG87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: September 3, 2014
This is version 45 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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