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Protein

Putative thymidine phosphorylase

Gene

BBta_3062

Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciBSP288000:GJBR-2911-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:BBta_3062
OrganismiBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Taxonomic identifieri288000 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000000246 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511Putative thymidine phosphorylasePRO_0000314697Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi288000.BBta_3062.

Structurei

3D structure databases

ProteinModelPortaliA5EG87.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
IPR000053. Thymidine/pyrmidine_PPase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5EG87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTIDSARPQ LKIRSVALDT GRENVVVISR RSRALRPEVF SGFSRVELRC
60 70 80 90 100
NSRTLLATLL ITDDDALVGP DEIGLSQPAL RRFAEPAGTF ATVSPATPPD
110 120 130 140 150
SLEAVRAKIR GETLSDQAIS AVIDDLAHYR YSDMEIAAFL IGSASFMTSG
160 170 180 190 200
ELLALTRAMA NAGTQLKWPE PVVVDKHCIG GIPGNRTSMV VVPIVAAHGL
210 220 230 240 250
TIPKTSSRAI TSPAGTADTM EVLARVNVGA EEMKSIVAAC NGCVIWGGHV
260 270 280 290 300
NLSPADDILI SVERPLSLDT REQMVASILS KKLAAGSTHL LLDLPVGPTA
310 320 330 340 350
KLSSGAEAMR LRKLFEFVGD RFGLNVEVIT TDGRQPIGNG IGPVLEARDV
360 370 380 390 400
MAVLGNEPGA PADLREKSLR LAAHLLEYDP KLRGGAGYQR ARELLDSGAA
410 420 430 440 450
LKQMQKIIDA QGPTTSRNEL GDLAFDVKAG RDGIVSAIDC LRLNRLARTA
460 470 480 490 500
GAPINKGAGI RLFKKIGDRV DQGEPLYRVF TCDPSEHDLA VAAAAADHGY
510
GFADEPNGHQ R
Length:511
Mass (Da):54,383
Last modified:January 15, 2008 - v2
Checksum:i02CE1A5A2442C6FD
GO

Sequence cautioni

The sequence ABQ35181.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000494 Genomic DNA. Translation: ABQ35181.1. Different initiation.
RefSeqiWP_012043201.1. NC_009485.1.
YP_001239087.1. NC_009485.1.

Genome annotation databases

EnsemblBacteriaiABQ35181; ABQ35181; BBta_3062.
KEGGibbt:BBta_3062.
PATRICi21206947. VBIBraSp29847_3156.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000494 Genomic DNA. Translation: ABQ35181.1. Different initiation.
RefSeqiWP_012043201.1. NC_009485.1.
YP_001239087.1. NC_009485.1.

3D structure databases

ProteinModelPortaliA5EG87.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi288000.BBta_3062.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ35181; ABQ35181; BBta_3062.
KEGGibbt:BBta_3062.
PATRICi21206947. VBIBraSp29847_3156.

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OrthoDBiEOG61ZTGG.

Enzyme and pathway databases

BioCyciBSP288000:GJBR-2911-MONOMER.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
IPR000053. Thymidine/pyrmidine_PPase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BTAi1 / ATCC BAA-1182.

Entry informationi

Entry nameiTYPH_BRASB
AccessioniPrimary (citable) accession number: A5EG87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: April 1, 2015
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.