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A5EG02 (A5EG02_BRASB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH2 HAMAP MF_00191
Ordered Locus Names:BBta_2972
OrganismBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP] EMBL ABQ35096.1
Taxonomic identifier288000 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
A5EG02 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: CE8413AFE2C8D558

FASTA31433,757
        10         20         30         40         50         60 
MTDRRPLQIY LAQPRGFCAG VVRAIEIVER ALEKYGRPVY VRHEIVHNKY VVESLKAKGA 

        70         80         90        100        110        120 
IFVEDLSEVP PRAVTVFSAH GVARSVEEEA AARGLPVLNA TCPLVTKVHN QGKRYMSKGR 

       130        140        150        160        170        180 
TLVLIGHAGH PEVEGTMGQV PGPVHLVQNV ADVAALPLPS DTPVAYITQT TLSVDDTKDI 

       190        200        210        220        230        240 
ISALQARFTD LQGPDIRDIC YATQNRQSAV WDLSKLVDVI LVVGAANSSN SNRLREIGTE 

       250        260        270        280        290        300 
AGVASYLVAD GSELNPEWLK GARAVGITAG ASAPEVLVDD VIEALRRIGP VEVAVVPGRE 

       310 
ENIEFRLPAE LVAG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000494 Genomic DNA. Translation: ABQ35096.1.
RefSeqYP_001239002.1. NC_009485.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA5EG02.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5152996.
GenomeReviewsGene locus BBta_2972 in contig CP000494_GR.
KEGGbbt:BBta_2972.
PATRIC21206769. VBIBraSp29847_3067.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0761.
HOGENOMHBG335228.
OMAHNQGKRY.
ProtClustDBPRK01045.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5EG02_BRASB
AccessionPrimary (citable) accession number: A5EG02
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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