Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A5E993

- RBL1A_BRASB

UniProt

A5E993 - RBL1A_BRASB

Protein

Ribulose bisphosphate carboxylase large chain 1

Gene

cbbL1

Organism
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

    Catalytic activityi

    2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
    3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

    Cofactori

    Binds 1 magnesium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei127 – 1271Substrate; in homodimeric partnerUniRule annotation
    Binding sitei177 – 1771SubstrateUniRule annotation
    Active sitei179 – 1791Proton acceptorUniRule annotation
    Binding sitei181 – 1811SubstrateUniRule annotation
    Metal bindingi205 – 2051Magnesium; via carbamate groupUniRule annotation
    Metal bindingi207 – 2071MagnesiumUniRule annotation
    Metal bindingi208 – 2081MagnesiumUniRule annotation
    Active sitei297 – 2971Proton acceptorUniRule annotation
    Binding sitei298 – 2981SubstrateUniRule annotation
    Binding sitei330 – 3301SubstrateUniRule annotation
    Sitei337 – 3371Transition state stabilizerUniRule annotation
    Binding sitei382 – 3821SubstrateUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. monooxygenase activity Source: UniProtKB-KW
    3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. reductive pentose-phosphate cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    Lyase, Monooxygenase, Oxidoreductase

    Keywords - Biological processi

    Calvin cycle, Carbon dioxide fixation, Photosynthesis

    Keywords - Ligandi

    Magnesium, Metal-binding

    Enzyme and pathway databases

    BioCyciBSP288000:GJBR-438-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribulose bisphosphate carboxylase large chain 1UniRule annotation (EC:4.1.1.39UniRule annotation)
    Short name:
    RuBisCO large subunit 1UniRule annotation
    Gene namesi
    Name:cbbL1UniRule annotation
    Ordered Locus Names:BBta_0451
    OrganismiBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
    Taxonomic identifieri288000 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
    ProteomesiUP000000246: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 488488Ribulose bisphosphate carboxylase large chain 1PRO_0000299958Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei205 – 2051N6-carboxylysineUniRule annotation

    Interactioni

    Subunit structurei

    Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

    Protein-protein interaction databases

    STRINGi288000.BBta_0451.

    Structurei

    3D structure databases

    ProteinModelPortaliA5E993.
    SMRiA5E993. Positions 15-481.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1850.
    HOGENOMiHOG000230831.
    KOiK01601.
    OMAiCTPLKQA.
    OrthoDBiEOG6ZKXMS.

    Family and domain databases

    Gene3Di3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPiMF_01338. RuBisCO_L_type1.
    InterProiIPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view]
    PfamiPF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5E993-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNEALKSLTV TGKERYKSGV LEYKRMGYWE PDYEPKDTDV IALFRVTPQN    50
    GVDPIEASAA VAGESSTATW TVVWTDRLTA AEKYRAKCYR VDPVPNTPGS 100
    YFAYIAYDLD LFEPGSIANL SASIIGNVFG FKPLKALRLE DMRFPVAYVK 150
    TFQGPATGIV VERERLDKFG RPLLGATVKP KLGLSGRNYG RVVYEALKGG 200
    LDFTKDDENT NSQPFMHWRD RFLYCMEAVN KAQAATGEVK GTYLNVTAAT 250
    MEDMYERAEF AKELGSVIIM IDLVIGYTAI QSMAKWARRN DMILHLHRAG 300
    HGTYTRQKSH GVSFRVIAKW MRLAGVDHIH AGTVVGKLEG DPNTTRGYYD 350
    ICREDHNPMA LEYGLFFEQH WASLNKLMPV ASGGIHAGQM HQLLNYLGED 400
    VVLQFGGGTI GHPLGIQAGA TANRVALEAM ILARNEGRDY VHEGPEILAK 450
    AAATCTPLKQ ALDVWKNVTF NYDSTDTPDF VPTAAVTA 488
    Length:488
    Mass (Da):54,042
    Last modified:June 12, 2007 - v1
    Checksum:i04A753A5D99867E3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000494 Genomic DNA. Translation: ABQ32737.1.
    RefSeqiWP_012040789.1. NC_009485.1.
    YP_001236643.1. NC_009485.1.

    Genome annotation databases

    EnsemblBacteriaiABQ32737; ABQ32737; BBta_0451.
    GeneIDi5154513.
    KEGGibbt:BBta_0451.
    PATRICi21201912. VBIBraSp29847_0655.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000494 Genomic DNA. Translation: ABQ32737.1 .
    RefSeqi WP_012040789.1. NC_009485.1.
    YP_001236643.1. NC_009485.1.

    3D structure databases

    ProteinModelPortali A5E993.
    SMRi A5E993. Positions 15-481.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 288000.BBta_0451.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABQ32737 ; ABQ32737 ; BBta_0451 .
    GeneIDi 5154513.
    KEGGi bbt:BBta_0451.
    PATRICi 21201912. VBIBraSp29847_0655.

    Phylogenomic databases

    eggNOGi COG1850.
    HOGENOMi HOG000230831.
    KOi K01601.
    OMAi CTPLKQA.
    OrthoDBi EOG6ZKXMS.

    Enzyme and pathway databases

    BioCyci BSP288000:GJBR-438-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPi MF_01338. RuBisCO_L_type1.
    InterProi IPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view ]
    Pfami PF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BTAi1 / ATCC BAA-1182.

    Entry informationi

    Entry nameiRBL1A_BRASB
    AccessioniPrimary (citable) accession number: A5E993
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3