A5E987 (F16A1_BRASB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fructose-1,6-bisphosphatase class 1 1
Short name=FBPase class 1 1
EC=3.1.3.11

Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1

Gene names

Name:	fbp1
Ordered Locus Names:	BBta_0445

Organism

Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP]

Taxonomic identifier

288000 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; Calvin cycle. HAMAP MF_01855
Subunit structure	Homotetramer By similarity. HAMAP MF_01855
Subcellular location	Cytoplasm Potential HAMAP MF_01855.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 338	338	Fructose-1,6-bisphosphatase class 1 1 HAMAP MF_01855		PRO_0000364473
Regions
	Region	110 – 113	4	Substrate binding By similarity
Sites
	Metal binding	88	1	Magnesium 1 By similarity
	Metal binding	107	1	Magnesium 1 By similarity
	Metal binding	107	1	Magnesium 2 By similarity
	Metal binding	109	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	110	1	Magnesium 2 By similarity
	Metal binding	268	1	Magnesium 2 By similarity
	Binding site	196	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5E987 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: B0CA50022FCFB979	FASTA	338	36,736
	10 20 30 40 50 60 MTAPEGTLES FLEGDCSVSE PLAITVTALA FVAETLAGVI SSGPLNGRLG EEVGANSDGD 70 80 90 100 110 120 RQKKLDVVAD ELFAGALAPT PVRWYASEER PTAEMLNPEG TLALAIDPLD GSSNIDVNIS 130 140 150 160 170 180 IGTIFSVFEA KESGVESFLR PGREQIAAGY VVYGPQTVFI LATRTTLAQF VLHRGHFFLV 190 200 210 220 230 240 SDSLRIPDRT TEFAINASNY RHWSRPIRAF VDDCIAGDEG PWGENFNMRW VASLVAETHR 250 260 270 280 290 300 ILTRGGIFLY PADARRGYGQ GRLRLVYECA PIAFIVERAG GKATDGIDRI LDLTPSELHQ 310 320 330 RTPLVFGTAE KVSQVCAYHD LPESEVSPLF GTRGLFRA

References

[1]

"Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia." Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C., Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L., Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z. , Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E., Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G., Emerich D., Vermeglio A., Medigue C., Sadowsky M. Science 316:1307-1312(2007) [PubMed: 17540897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BTAi1 / ATCC BAA-1182.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000494 Genomic DNA. Translation: ABQ32731.1.
RefSeq	YP_001236637.1. NC_009485.1.
3D structure databases
ProteinModelPortal	A5E987.
ModBase	Search...
Protein-protein interaction databases
STRING	A5E987.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5154743.
GenomeReviews	Gene locus BBta_0445 in contig CP000494_GR.
KEGG	bbt:BBta_0445.
PATRIC	21201900. VBIBraSp29847_0649.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0158.
HOGENOM	HBG731261.
OMA	AMSISPE.
ProtClustDB	CLSK841466.
Family and domain databases
HAMAP	MF_01855. FBPase_class1. [Tree]
InterPro	IPR000146. FBPase_class-1/SBPase. IPR020548. Fructose_bisphosphatase_AS. [Graphical view]
KO	K03841.
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PIRSF	PIRSF000904. FBPtase_SBPase. 1 hit.
PRINTS	PR00115. F16BPHPHTASE.
PROSITE	PS00124. FBPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16A1_BRASB

Accession

Primary (citable) accession number: A5E987

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program