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A5E8Y1 (A5E8Y1_BRASB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acsA HAMAP MF_01123
Ordered Locus Names:BBta_0333
OrganismBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP] EMBL ABQ32625.1
Taxonomic identifier288000 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length650 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5141 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6061N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
A5E8Y1 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 89185715FDFE36EA

FASTA65072,111
        10         20         30         40         50         60 
MSEKIYDVPA EWAKRAFVDD AKYQEMYARS IKDPNGFWAE QAKRVDWVKA PTIIENVSYA 

        70         80         90        100        110        120 
PGNISIKWFE DGVLNAAYNC IDRHLATRAN QTAIIWEGDD PSQSKNITYR ELHDEVCKMA 

       130        140        150        160        170        180 
NILRNRNVKK GDRVTIYLPM IPEAAYAMLA CARIGAIHSV VFAGFSPDSL AQRIKDCDSK 

       190        200        210        220        230        240 
VVITADEGLR GGRKVPLKAN VDAALNKVDN VDWVVVVKRT GGKVEMNPTR DLWYHEAAEM 

       250        260        270        280        290        300 
VTTECPCEPM HAEDPLFILY TSGSTGQPKG VLHTTGGYLV YAAMTHQYVF DYHEGDVYWC 

       310        320        330        340        350        360 
TADVGWVTGH SYILYGPLAN GAVTLMFEGV PNYPDNSRFW NVIDKHKVNI FYTAPTAIRA 

       370        380        390        400        410        420 
LMQGGDAPVT KTSRASLRLL GSVGEPINPE AWEWYHRVVG GGRCPIVDTW WQTETGGILI 

       430        440        450        460        470        480 
TPLPGATKLK PGSATRPFFG VVPEIVDADG KTLEGATEGN LCLTRSWPGQ MRTVYGDHAR 

       490        500        510        520        530        540 
FEMTYFSTYK GKYFTGDGCR RDADGYYWIT GRVDDVINVS GHRMGTAEVE SALVAHAKVS 

       550        560        570        580        590        600 
EAAVVGYPHD IKGQGIYAYV TLMAGETPSE ELRKELVAWV RKEIGPIASP DQIQFAPGLP 

       610        620        630        640        650 
KTRSGKIMRR ILRKIAEDEP SALGDTSTLA DPGVVDDLVQ HRQNRKEKQA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000494 Genomic DNA. Translation: ABQ32625.1.
RefSeqYP_001236531.1. NC_009485.1.

3D structure databases

ProteinModelPortalA5E8Y1.
SMRA5E8Y1. Positions 8-643.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5E8Y1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5153708.
GenomeReviewsGene locus BBta_0333 in contig CP000494_GR.
KEGGbbt:BBta_0333.
PATRIC21201680. VBIBraSp29847_0540.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0365.
HOGENOMHBG547964.
OMAWNCIERN.
ProtClustDBPRK00174.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5E8Y1_BRASB
AccessionPrimary (citable) accession number: A5E8Y1
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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