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A5E8B1 (AROA_BRASB) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:BBta_0105
OrganismBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP]
Taxonomic identifier288000 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4454453-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_0000325336

Sequences

Sequence LengthMass (Da)Tools
A5E8B1 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: EAE6AD7B97A85711

FASTA44546,303
        10         20         30         40         50         60 
MSAPAAPIPL ESRASGPLSG TLRVPGDKSI SHRALILGAL SVGETRISGL LEGEDVLNTA 

        70         80         90        100        110        120 
QAMRALGAKV ERHGDFAWTV HGVGVGGFAQ PAATLDFGNS GTGCRLVMGA VAGCPITAVF 

       130        140        150        160        170        180 
DGDASLRSRP MRRILDPLEL IGAKVTASAE GGKLPLTLQG ASNPVPVVYR TPVASAQIKS 

       190        200        210        220        230        240 
AVLLAGLAAP GVTTVIEQEA SRDHTELMLK HFGAEIVTTL EGTHGRRIAL TGQPELHGAP 

       250        260        270        280        290        300 
VIVPADPSSA AFPLVAALIV DGSDLVLSDV MTNPLRTGLF ATLREMGASI EEDDVRGDAG 

       310        320        330        340        350        360 
EPMVRLRVRA SKLRGVEVPP ERAPSMIDEY LVLAVAAAYA EGTTIMRGLH ELRVKESDRL 

       370        380        390        400        410        420 
EATAAMLRVN GVKVEISDDD LIVEGRGHVP GGGLVATHMD HRIAMSALVM GLASDKPVKV 

       430        440 
DDTAFIATSF PDFVPLMCKA GADFA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000494 Genomic DNA. Translation: ABQ32405.1.
RefSeqYP_001236311.1. NC_009485.1.

3D structure databases

ProteinModelPortalA5E8B1.
SMRA5E8B1. Positions 9-444.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5E8B1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5155296.
GenomeReviewsGene locus BBta_0105 in contig CP000494_GR.
KEGGbbt:BBta_0105.
PATRIC21201208. VBIBraSp29847_0309.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_BRASB
AccessionPrimary (citable) accession number: A5E8B1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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