Skip Header

Contribute Send feedback
Read comments (?) or add your own

A5E819 (A5E819_BRASB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA gyrase subunit B HAMAP MF_01898
EC=5.99.1.3 HAMAP MF_01898
Gene names
Name:gyrB HAMAP MF_01898 EMBL ABQ32313.1
Ordered Locus Names:BBta_0008
OrganismBradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) [Complete proteome] [HAMAP] EMBL ABQ32313.1
Taxonomic identifier288000 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length812 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. HAMAP MF_01898

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS002288 HAMAP MF_01898

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898

Subcellular location

Cytoplasm By similarity HAMAP MF_01898.

Sequence similarities

Belongs to the type II topoisomerase family. HAMAP MF_01898

Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Sequences

Sequence LengthMass (Da)Tools
A5E819 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 69E0FBE4DA8CDD28

FASTA81289,828
        10         20         30         40         50         60 
MTEPARQTIA DNEPATANDY GAESIRVLKG LDAVRKRPGM YIGDTDDGSG LHHMVYEVVD 

        70         80         90        100        110        120 
NAIDEALAGY ASRVEVVLNA DNSVTVRDDG RGIPVDIHKG EGVSAAEVIM TQLHAGGKFD 

       130        140        150        160        170        180 
QNSYKVSGGL HGVGVSVVNA LSSKLQLRIW REDKEHLIEF AHGDAVAPLK VVGEAQGRRG 

       190        200        210        220        230        240 
TEVTFLASTE TFKMVEYDYA TLEHRLRELA FLNSGVHIVL SDMRHAVEKR EEMFYSGGVE 

       250        260        270        280        290        300 
EFVRYLDRNK KAIVPSPIMV RSEVNGITVE AALWWNDSYH ENVLCFTNNI PQRDGGTHLA 

       310        320        330        340        350        360 
GFRGALTRQV NGYADAHAKK EKIALTGDDC REGLTAVLSV KVPDPKFSSQ TKDKLVSSEV 

       370        380        390        400        410        420 
RPVVENVINE ALSAWFEEHP SEAKTVVGKV IQAAAAREAA RKARELTRKN PLNNIASLPG 

       430        440        450        460        470        480 
KLADCQEKDP AKSELFIVEG DSAGGSAKQG RNREFQAVLP LRGKILNVER VRPDKMLSSE 

       490        500        510        520        530        540 
QIGTLITALG TGISDDFSID KLRYHKIIVM TDADVDGAHI RTLLLTFFYR QMRQIIDRGH 

       550        560        570        580        590        600 
LYIAQPPLYK VTRGKSEQYL KDERALEDYL IGTGLDDCVF KSAEGEERKG RDLLALVEEA 

       610        620        630        640        650        660 
RIVRNILRNL HSRYDRTVVE QAAIAGVLRA DITRDIATAD AAAEYIAKRL DVLADEVERG 

       670        680        690        700        710        720 
WIGHFVEGQG FTFERTVRGV KDVAVIDDAL LASADARKLD DYAARLQEAY AKPGFLRRGD 

       730        740        750        760        770        780 
APTVIHGPID LFEAVTDAGR KGIAMQRYKG LGEMNPQQLW ETTLDTEART LLQVKVKEVD 

       790        800        810 
EADDIFTKLM GDVVEPRREF IQDNSLSANV DV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000494 Genomic DNA. Translation: ABQ32313.1.
RefSeqYP_001236219.1. NC_009485.1.

3D structure databases

ProteinModelPortalA5E819.
SMRA5E819. Positions 25-391.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5E819.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5156080.
GenomeReviewsGene locus BBta_0008 in contig CP000494_GR.
KEGGbbt:BBta_0008.
PATRIC21201026. VBIBraSp29847_0218.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0187.
HOGENOMHBG304889.
OMADCSSRDP.
ProtClustDBPRK14939.

Family and domain databases

HAMAPMF_01898. GyrB.
[Tree]
InterProIPR003594. ATPase-like_ATP-bd.
IPR011557. GyrB.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR001241. Topo_IIA.
IPR013759. Topo_IIA_B/N_ab.
IPR002288. Topo_IIA_B_C.
IPR013506. Topo_IIA_bsu_dom2.
IPR013760. Topo_IIA_cen.
IPR018522. TopoIIA_CS.
IPR006171. Toprim_domain.
[Graphical view]
Gene3DG3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KOK02470.
PfamPF00204. DNA_gyraseB. 1 hit.
PF00986. DNA_gyraseB_C. 1 hit.
PF02518. HATPase_c. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSPR00418. TPI2FAMILY.
SMARTSM00387. HATPase_c. 1 hit.
SM00433. TOP2c. 1 hit.
[Graphical view]
SUPFAMSSF55874. ATP_bd_ATPase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01059. GyrB. 1 hit.
PROSITEPS00177. TOPOISOMERASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5E819_BRASB
AccessionPrimary (citable) accession number: A5E819
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info