A5E343 (A5E343_LODEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase RuleBase RU003838
EC=2.4.2.11 RuleBase RU003838

Gene names

ORF Names:

LELG_04030 EMBL EDK45851.1

Organism

Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus) [Complete proteome]

Taxonomic identifier

379508 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Lodderomyces

Protein attributes

Sequence length	416 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. RuleBase RU003838
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838
Sequence similarities	Belongs to the NAPRTase family. RuleBase RU003838

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis RuleBase RU003838
Molecular function	Glycosyltransferase RuleBase RU003838 EMBL EDK45851.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: EC nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5E343 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 3B710BD8D7783BBA	FASTA	416	47,757
	10 20 30 40 50 60 MTETIEPVIT SLLDTDLYKI FMHAAVFKHF PNIPVRYKYT NRTPELQLNA PAINWLKQQV 70 80 90 100 110 120 EYLGELEFSV KEIEYLRKTL PQLSDEYLAY LQTFKLDPQS QIKYIESDNG DFALEIVGNW 130 140 150 160 170 180 DQTILYEIPL LALVSEAYFK YVDTDWDYSG QYELAKSKVL DLISNGCSFS EFGTRRRRSF 190 200 210 220 230 240 KTQEIVVDAI KEVFEETHSK HIAGTSNVLL AMQKNLAPVG TVAHEWYMGI AAITQNYKRA 250 260 270 280 290 300 NTTAMDYWLD TFGKQYAGLA LTDTFGTDNY LEQFKSPYAE VYAGVRQDSG DPVLYAEKMA 310 320 330 340 350 360 KHYKSLGLKD KVICFSDSLN IEKCLAYKQK ADELGLKSTF GVGTFFTNDF QNKTTRKKSQ 370 380 390 400 410 PLNIVIKLKE ANGQHCIKIS DNVGKNMGDK ETVEKVKKEL GYVERTWEEG DEAHRW

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed: 19465905] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11503 / CBS 2605 / IFO 1676 / JCM 1781 / NRRL YB-4239 and ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH981528 Genomic DNA. Translation: EDK45851.1.
RefSeq	XP_001524998.1. XM_001524948.1.
3D structure databases
ProteinModelPortal	A5E343.
SMR	A5E343. Positions 5-403.
ModBase	Search...
Protein-protein interaction databases
STRING	A5E343.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5231902.
KEGG	lel:LELG_04030.
Phylogenomic databases
OMA	HQFPQTH.
OrthoDB	EOG479JGB.
Family and domain databases
HAMAP	MF_00570. NAPRTase. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
KO	K00763.
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5E343_LODEL

Accession

Primary (citable) accession number: A5E343

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)