A5E2Z4 (A5E2Z4_LODEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Delta-1-pyrroline-5-carboxylate dehydrogenase EMBL EDK45802.1

Gene names

ORF Names:

LELG_03981 EMBL EDK45802.1

Organism

Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus) [Complete proteome]

Taxonomic identifier

379508 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Lodderomyces

Protein attributes

Sequence length	605 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5E2Z4 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 22BB8ED7F2B656F7	FASTA	605	66,696
	10 20 30 40 50 60 MLRVNNVRMF SKVVLRATSG TGKARSLSRL SLATTATKTN IATPCLASAG VRFASQLSHV 70 80 90 100 110 120 KTPPNLQNEP VKNFGFNDVK DWDLLRASLT KFTDDGALKV PIVIGGEKIY RDDIKPQLNP 130 140 150 160 170 180 ADHSQNLADV SQATVEDVRA AIDAAKAAKL KWSQTSWTDR AAIFLKAADL ISTKYRYDIL 190 200 210 220 230 240 AATMLGQGKN VYQAEIDSIA ELIDFFKFNV KYAEELYGQQ PLQTSPGVWN RAEYRPLEGF 250 260 270 280 290 300 VYAVTPFNFT AIAANLVGAP ALMGNTVVWK PSATAALSNY LLLTILEEAG LPKGVINFIP 310 320 330 340 350 360 GDPVEVTDTV LNDKDFAALH FTGSTDVFKH LYHKISTGVL QDKYRDFPRI VGETGGKNFH 370 380 390 400 410 420 LIHPSASLHH SALSTLRGAF EYQGQKCSAT SRLYVPESLW PEFRDILAGQ MSQISVGNTS 430 440 450 460 470 480 SSTSLNSFVG PVIHEQSFDK LANAIDQAKN DPELEIISGG SYDKSKGFYV QPTLIKTTNP 490 500 510 520 530 540 EHEFLTKEFF GPILTAYVYP DSQYEQIIQS IDSVTKYGLT GSIFARDRDA IRLAEENLRY 550 560 570 580 590 600 SAGNFYINDK STGAVVGQQW FGGARASGTN DKAGSANILS RFVSVRNIKE NFYELTDFRY PSNYQ

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed: 19465905] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11503 / CBS 2605 / IFO 1676 / JCM 1781 / NRRL YB-4239 and ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH981528 Genomic DNA. Translation: EDK45802.1.
RefSeq	XP_001524949.1. XM_001524899.1.
3D structure databases
ProteinModelPortal	A5E2Z4.
ModBase	Search...
Protein-protein interaction databases
STRING	A5E2Z4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5232198.
KEGG	lel:LELG_03981.
Phylogenomic databases
OMA	STGVFQQ.
OrthoDB	EOG4350FG.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5E2Z4_LODEL

Accession

Primary (citable) accession number: A5E2Z4

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	November 16, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)