A5E2A2 (A5E2A2_LODEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Homoserine kinase EMBL EDK45560.1

Gene names

ORF Names:

LELG_03739 EMBL EDK45560.1

Organism

Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus) [Complete proteome]

Taxonomic identifier

379508 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Lodderomyces

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003564 Nucleotide-binding
Molecular function	Kinase RuleBase RU003564 EMBL EDK45560.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	threonine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5E2A2 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 082A52DF7B6C415A	FASTA	352	38,690
	10 20 30 40 50 60 MFESFEIKVP ASSANIGPGF DVLGIGLELY LSIKVIIDKN VDTSSDPHNA KLSYEGSLAE 70 80 90 100 110 120 KVPLRSDKNL VTQTALYVLR TVGVDKFPLG TQIFVNNPIP LGRGLGSSAS AIVGGIYLGN 130 140 150 160 170 180 AIGKLNLSKE RMLDYCLMIE RHPDNIAAAM LGGFIGSYLN ELDKADAEHT QVPLDYILPK 190 200 210 220 230 240 PDTPSDVIVR EKPPMNIGEY MKYNWNKKIK CVVIIPNFEL STDKSRAVLP QSYTRPDIIY 250 260 270 280 290 300 NLQRIAVLTA ALTQDPPNHK LIYQSMRDKI HQPYRTVLIP GLDQVLEQVV PAKQPGLCGI 310 320 330 340 350 CLSGAGPTIL CLATEGFEDI AHEVTNIFDS EGIKCDWKVL DLAYDGATLE YL

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed: 19465905] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11503 / CBS 2605 / IFO 1676 / JCM 1781 / NRRL YB-4239 and ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH981528 Genomic DNA. Translation: EDK45560.1.
RefSeq	XP_001524707.1. XM_001524657.1.
3D structure databases
ProteinModelPortal	A5E2A2.
ModBase	Search...
Protein-protein interaction databases
STRING	A5E2A2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5232053.
KEGG	lel:LELG_03739.
Phylogenomic databases
OMA	DRLHQPY.
OrthoDB	EOG4B8NNT.
Family and domain databases
HAMAP	MF_00384. Homoser_kinase. [Tree]
InterPro	IPR006204. GHMP_kinase. IPR013750. GHMP_kinase_C. IPR006203. GHMP_knse_ATP-bd_CS. IPR000870. Homoserine_kinase. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KO	K00872.
Pfam	PF08544. GHMP_kinases_C. 1 hit. PF00288. GHMP_kinases_N. 1 hit. [Graphical view]
PIRSF	PIRSF000676. Homoser_kin. 1 hit.
PRINTS	PR00958. HOMSERKINASE.
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00191. ThrB. 1 hit.
PROSITE	PS00627. GHMP_KINASES_ATP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5E2A2_LODEL

Accession

Primary (citable) accession number: A5E2A2

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)