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Protein

Hexokinase

Gene

LELG_03305

Organism
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:LELG_03305Imported
OrganismiLodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)Imported
Taxonomic identifieri379508 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeLodderomyces
ProteomesiUP000001996 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi36914.A5E118.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

InParanoidiA5E118.
KOiK00844.
OMAiTHANTVI.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5E118-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSEKLEVA VRDIENDFYI DDDFLIKASQ YFEESMRAGL QAPEQDRAHM
60 70 80 90 100
PMIPTYVTSL PTGKEKGLFL AADLGGTNFR VCSVDLKGDH TFDLKQSKFR
110 120 130 140 150
IPLDLMKGDH ADDLFRFLAT KIAAFLDENH QDCRVKGSKP LKLGFTFSFP
160 170 180 190 200
VDQTALNRGT LLRWTKSFDI PDTVGRDVVQ LLQANLTVLE VNVDVVALAN
210 220 230 240 250
DTVGTLLSRS YANNPEYTHA NTVIGLIFGT GTNGAYYESF DRIPKLKNKP
260 270 280 290 300
EGAKGMVINT EWGSFDNELK ILPNTLYDKI VDSETANKGY HMFEKRVSGL
310 320 330 340 350
FLGEILRVAL LDLFEKGLIF QELYKERGGS LPHRLITPWQ LDSEVLSYIQ
360 370 380 390 400
IDDSTALKMS ELILQNTLRL PTTADERVVI QRITRAISKR AAQLAAIPIA
410 420 430 440 450
TIIRETKDLY ADDERDFEVG CDGSVIEFYP GFRDEIMKAF NVIDPLKGSR
460 470
KKVHLKIAKD GSGVGAALIA ATTD
Length:474
Mass (Da):52,975
Last modified:June 11, 2007 - v1
Checksum:i59CC0909AE2131B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH981527 Genomic DNA. Translation: EDK45126.1.
RefSeqiXP_001525377.1. XM_001525327.1.

Genome annotation databases

GeneIDi5232353.
KEGGilel:LELG_03305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH981527 Genomic DNA. Translation: EDK45126.1.
RefSeqiXP_001525377.1. XM_001525327.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi36914.A5E118.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5232353.
KEGGilel:LELG_03305.

Phylogenomic databases

InParanoidiA5E118.
KOiK00844.
OMAiTHANTVI.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239Imported.

Entry informationi

Entry nameiA5E118_LODEL
AccessioniPrimary (citable) accession number: A5E118
Entry historyi
Integrated into UniProtKB/TrEMBL: June 11, 2007
Last sequence update: June 11, 2007
Last modified: March 31, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.