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Protein

DNA ligase

Gene

LELG_02126

Organism
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:LELG_02126Imported
OrganismiLodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)Imported
Taxonomic identifieri379508 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeLodderomyces
ProteomesiUP000001996: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi36914.A5DXN9.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiA5DXN9.
KOiK10747.
OMAiLACYDEQ.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5DXN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLLRRNLIK TEKLVKLKCL GCLKNTTMAQ QQTLGRFFGS SASIQASKPK
60 70 80 90 100
AKAKAEKTTT SPTKSAPIKL TKRANSLDKN GDVTSSLSAK KRKVTASNQD
110 120 130 140 150
YEDANLSLNN DRSSQENNSE EMDSEMTTEN NEKEKEEAKS LIKLSEEQQK
160 170 180 190 200
NKTQGSENQK SLATAKIPYS LLTDIFESIE HESSRLKITA IISQFFLEIL
210 220 230 240 250
QQQQQEGDVS KLVKIVYLFI NRLGPDYEPD LELGLGETLL IKAISECYGR
260 270 280 290 300
TPTKIKQDYK EVGDLGLVAQ KSRSGQPTMF KSADLDVDTV FENLTKIAKS
310 320 330 340 350
TGKDSQLKKI GIINKMLTAC QLKHNEAKFL IRSLEGKLRI GLAEKTVLVG
360 370 380 390 400
LAQAFVNFEA WKNNGNNKRI DPAKLVEAED TMREAFTRIP NYQVLIENAY
410 420 430 440 450
KYGIFNLLDH SQLTPGIPLK PMLAKPTKSM SEVLDRFQDE KFTCEYKYDG
460 470 480 490 500
ERAQVHLSSD GQVRIYSRNS EDMSQRYPDL ISIIKEFSKT QEHTSMILDC
510 520 530 540 550
EAVAWDRVQK KILPFQVLST RKRKDVNEKD ITVFICLFAF DILYYNNTSL
560 570 580 590 600
ITKSLKERRE IMFKHLTPIE GKFQFATSKD STSLEVLQQF LDQSVKDSCE
610 620 630 640 650
GLMVKMLEGT ESYYEPSKRS RNWLKLKKDY LEGVGDSLDL VVIGAYSGRG
660 670 680 690 700
KRTGTYGGFL LASYNQDTGD LETTCKIGTG FSEEDLAKLY ERLHPTEIPK
710 720 730 740 750
AKEYFVYDKT NSNAVPDVWF EPSVLFEVLT ADLSLSPIYK AAHSEYGKGI
760 770 780
SLRFPRFLRL RDDKDIEDAT SSTQVSEFYQ RQAHLL
Length:786
Mass (Da):89,154
Last modified:June 12, 2007 - v1
Checksum:iBB98B5461F68379A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH981525 Genomic DNA. Translation: EDK43947.1.
RefSeqiXP_001527297.1. XM_001527247.1.

Genome annotation databases

GeneIDi5234261.
KEGGilel:LELG_02126.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH981525 Genomic DNA. Translation: EDK43947.1.
RefSeqiXP_001527297.1. XM_001527247.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi36914.A5DXN9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5234261.
KEGGilel:LELG_02126.

Phylogenomic databases

InParanoidiA5DXN9.
KOiK10747.
OMAiLACYDEQ.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239Imported.

Entry informationi

Entry nameiA5DXN9_LODEL
AccessioniPrimary (citable) accession number: A5DXN9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: March 4, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.