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Protein

DNA ligase

Gene

LELG_02126

Organism
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:LELG_02126Imported
OrganismiLodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)Imported
Taxonomic identifieri379508 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeLodderomyces
Proteomesi
  • UP000001996 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi379508.XP_001527297.1

Structurei

3D structure databases

ProteinModelPortaliA5DXN9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini528 – 665DNA_LIGASE_A3InterPro annotationAdd BLAST138

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili98 – 151Sequence analysisAdd BLAST54

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiA5DXN9
KOiK10747
OMAiWIKYKRD
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

A5DXN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLLRRNLIK TEKLVKLKCL GCLKNTTMAQ QQTLGRFFGS SASIQASKPK
60 70 80 90 100
AKAKAEKTTT SPTKSAPIKL TKRANSLDKN GDVTSSLSAK KRKVTASNQD
110 120 130 140 150
YEDANLSLNN DRSSQENNSE EMDSEMTTEN NEKEKEEAKS LIKLSEEQQK
160 170 180 190 200
NKTQGSENQK SLATAKIPYS LLTDIFESIE HESSRLKITA IISQFFLEIL
210 220 230 240 250
QQQQQEGDVS KLVKIVYLFI NRLGPDYEPD LELGLGETLL IKAISECYGR
260 270 280 290 300
TPTKIKQDYK EVGDLGLVAQ KSRSGQPTMF KSADLDVDTV FENLTKIAKS
310 320 330 340 350
TGKDSQLKKI GIINKMLTAC QLKHNEAKFL IRSLEGKLRI GLAEKTVLVG
360 370 380 390 400
LAQAFVNFEA WKNNGNNKRI DPAKLVEAED TMREAFTRIP NYQVLIENAY
410 420 430 440 450
KYGIFNLLDH SQLTPGIPLK PMLAKPTKSM SEVLDRFQDE KFTCEYKYDG
460 470 480 490 500
ERAQVHLSSD GQVRIYSRNS EDMSQRYPDL ISIIKEFSKT QEHTSMILDC
510 520 530 540 550
EAVAWDRVQK KILPFQVLST RKRKDVNEKD ITVFICLFAF DILYYNNTSL
560 570 580 590 600
ITKSLKERRE IMFKHLTPIE GKFQFATSKD STSLEVLQQF LDQSVKDSCE
610 620 630 640 650
GLMVKMLEGT ESYYEPSKRS RNWLKLKKDY LEGVGDSLDL VVIGAYSGRG
660 670 680 690 700
KRTGTYGGFL LASYNQDTGD LETTCKIGTG FSEEDLAKLY ERLHPTEIPK
710 720 730 740 750
AKEYFVYDKT NSNAVPDVWF EPSVLFEVLT ADLSLSPIYK AAHSEYGKGI
760 770 780
SLRFPRFLRL RDDKDIEDAT SSTQVSEFYQ RQAHLL
Length:786
Mass (Da):89,154
Last modified:June 12, 2007 - v1
Checksum:iBB98B5461F68379A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH981525 Genomic DNA Translation: EDK43947.1
RefSeqiXP_001527297.1, XM_001527247.1

Genome annotation databases

EnsemblFungiiEDK43947; EDK43947; LELG_02126
GeneIDi5234261
KEGGilel:LELG_02126

Similar proteinsi

Entry informationi

Entry nameiA5DXN9_LODEL
AccessioniPrimary (citable) accession number: A5DXN9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: March 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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