A5DXN9 (A5DXN9_LODEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

LELG_02126 EMBL EDK43947.1

Organism

Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus) [Complete proteome] EMBL EDK43947.1

Taxonomic identifier

379508 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Lodderomyces › Lodderomyces elongisporus

Protein attributes

Sequence length	786 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617 EMBL EDK43947.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5DXN9 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: BB98B5461F68379A	FASTA	786	89,154
	10 20 30 40 50 60 MHLLRRNLIK TEKLVKLKCL GCLKNTTMAQ QQTLGRFFGS SASIQASKPK AKAKAEKTTT 70 80 90 100 110 120 SPTKSAPIKL TKRANSLDKN GDVTSSLSAK KRKVTASNQD YEDANLSLNN DRSSQENNSE 130 140 150 160 170 180 EMDSEMTTEN NEKEKEEAKS LIKLSEEQQK NKTQGSENQK SLATAKIPYS LLTDIFESIE 190 200 210 220 230 240 HESSRLKITA IISQFFLEIL QQQQQEGDVS KLVKIVYLFI NRLGPDYEPD LELGLGETLL 250 260 270 280 290 300 IKAISECYGR TPTKIKQDYK EVGDLGLVAQ KSRSGQPTMF KSADLDVDTV FENLTKIAKS 310 320 330 340 350 360 TGKDSQLKKI GIINKMLTAC QLKHNEAKFL IRSLEGKLRI GLAEKTVLVG LAQAFVNFEA 370 380 390 400 410 420 WKNNGNNKRI DPAKLVEAED TMREAFTRIP NYQVLIENAY KYGIFNLLDH SQLTPGIPLK 430 440 450 460 470 480 PMLAKPTKSM SEVLDRFQDE KFTCEYKYDG ERAQVHLSSD GQVRIYSRNS EDMSQRYPDL 490 500 510 520 530 540 ISIIKEFSKT QEHTSMILDC EAVAWDRVQK KILPFQVLST RKRKDVNEKD ITVFICLFAF 550 560 570 580 590 600 DILYYNNTSL ITKSLKERRE IMFKHLTPIE GKFQFATSKD STSLEVLQQF LDQSVKDSCE 610 620 630 640 650 660 GLMVKMLEGT ESYYEPSKRS RNWLKLKKDY LEGVGDSLDL VVIGAYSGRG KRTGTYGGFL 670 680 690 700 710 720 LASYNQDTGD LETTCKIGTG FSEEDLAKLY ERLHPTEIPK AKEYFVYDKT NSNAVPDVWF 730 740 750 760 770 780 EPSVLFEVLT ADLSLSPIYK AAHSEYGKGI SLRFPRFLRL RDDKDIEDAT SSTQVSEFYQ RQAHLL

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH981525 Genomic DNA. Translation: EDK43947.1.
RefSeq	XP_001527297.1. XM_001527247.1.
3D structure databases
ProteinModelPortal	A5DXN9.
ModBase	Search...
Protein-protein interaction databases
STRING	36914.A5DXN9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5234261.
KEGG	lel:LELG_02126.
Phylogenomic databases
KO	K10747.
OMA	AQVACLY.
OrthoDB	EOG4RV60K.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5DXN9_LODEL

Accession

Primary (citable) accession number: A5DXN9

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	April 3, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)