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A5DXN9

- A5DXN9_LODEL

UniProt

A5DXN9 - A5DXN9_LODEL

Protein

DNA ligase

Gene

LELG_02126

Organism
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (12 Jun 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:LELG_02126Imported
    OrganismiLodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)Imported
    Taxonomic identifieri379508 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeLodderomyces
    ProteomesiUP000001996: Unassembled WGS sequence

    Interactioni

    Protein-protein interaction databases

    STRINGi36914.A5DXN9.

    Structurei

    3D structure databases

    ProteinModelPortaliA5DXN9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10747.
    OMAiMVKMLEG.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5DXN9-1 [UniParc]FASTAAdd to Basket

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    MHLLRRNLIK TEKLVKLKCL GCLKNTTMAQ QQTLGRFFGS SASIQASKPK    50
    AKAKAEKTTT SPTKSAPIKL TKRANSLDKN GDVTSSLSAK KRKVTASNQD 100
    YEDANLSLNN DRSSQENNSE EMDSEMTTEN NEKEKEEAKS LIKLSEEQQK 150
    NKTQGSENQK SLATAKIPYS LLTDIFESIE HESSRLKITA IISQFFLEIL 200
    QQQQQEGDVS KLVKIVYLFI NRLGPDYEPD LELGLGETLL IKAISECYGR 250
    TPTKIKQDYK EVGDLGLVAQ KSRSGQPTMF KSADLDVDTV FENLTKIAKS 300
    TGKDSQLKKI GIINKMLTAC QLKHNEAKFL IRSLEGKLRI GLAEKTVLVG 350
    LAQAFVNFEA WKNNGNNKRI DPAKLVEAED TMREAFTRIP NYQVLIENAY 400
    KYGIFNLLDH SQLTPGIPLK PMLAKPTKSM SEVLDRFQDE KFTCEYKYDG 450
    ERAQVHLSSD GQVRIYSRNS EDMSQRYPDL ISIIKEFSKT QEHTSMILDC 500
    EAVAWDRVQK KILPFQVLST RKRKDVNEKD ITVFICLFAF DILYYNNTSL 550
    ITKSLKERRE IMFKHLTPIE GKFQFATSKD STSLEVLQQF LDQSVKDSCE 600
    GLMVKMLEGT ESYYEPSKRS RNWLKLKKDY LEGVGDSLDL VVIGAYSGRG 650
    KRTGTYGGFL LASYNQDTGD LETTCKIGTG FSEEDLAKLY ERLHPTEIPK 700
    AKEYFVYDKT NSNAVPDVWF EPSVLFEVLT ADLSLSPIYK AAHSEYGKGI 750
    SLRFPRFLRL RDDKDIEDAT SSTQVSEFYQ RQAHLL 786
    Length:786
    Mass (Da):89,154
    Last modified:June 12, 2007 - v1
    Checksum:iBB98B5461F68379A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH981525 Genomic DNA. Translation: EDK43947.1.
    RefSeqiXP_001527297.1. XM_001527247.1.

    Genome annotation databases

    GeneIDi5234261.
    KEGGilel:LELG_02126.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH981525 Genomic DNA. Translation: EDK43947.1 .
    RefSeqi XP_001527297.1. XM_001527247.1.

    3D structure databases

    ProteinModelPortali A5DXN9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 36914.A5DXN9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5234261.
    KEGGi lel:LELG_02126.

    Phylogenomic databases

    KOi K10747.
    OMAi MVKMLEG.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239Imported.

    Entry informationi

    Entry nameiA5DXN9_LODEL
    AccessioniPrimary (citable) accession number: A5DXN9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 12, 2007
    Last sequence update: June 12, 2007
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3