ID   GSM1_LODEL              Reviewed;         707 AA.
AC   A5DU46;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   RecName: Full=Glucose starvation modulator protein 1;
GN   Name=GSM1; ORFNames=LELG_00882;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 /
RC   NRRL YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; CH981524; EDK42704.1; -; Genomic_DNA.
DR   RefSeq; XP_001528362.1; XM_001528312.1.
DR   AlphaFoldDB; A5DU46; -.
DR   GeneID; 5234865; -.
DR   KEGG; lel:LELG_00882; -.
DR   eggNOG; ENOG502R2ZP; Eukaryota.
DR   HOGENOM; CLU_010748_2_2_1; -.
DR   InParanoid; A5DU46; -.
DR   OMA; FCHEKHL; -.
DR   OrthoDB; 5483783at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; Zn(2)-C6 fungal-type DNA-binding domain; 1.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   InterPro; IPR001138; Zn2Cys6_DnaBD.
DR   PANTHER; PTHR47659:SF1; TRANSCRIPTION ACTIVATOR OF GLUCONEOGENESIS ERT1; 1.
DR   PANTHER; PTHR47659; ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; Zn2/Cys6 DNA-binding domain; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..707
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406487"
FT   DOMAIN          522..591
FT                   /note="PAS"
FT   DNA_BIND        20..48
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          63..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          154..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          260..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          621..659
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..122
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..177
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   707 AA;  78473 MW;  53B59B457AD67831 CRC64;
     MTKRLTPQEK LSRKPASRAC TFCHQKHLQC SNERPCKNCV KRNIADQCQD ITRKRVKYLT
     GANSKAVAAA TTPEATTTTP KRKQKRSVKG SPSISFPSSS ISPINTSTFD TNGHPNGHPN
     DLLRQSLEAS QAGQAQAPSL LEIQGPFPQM QTLQPTHTVA SETSSSYSQV QPQHHPESSV
     PPSAPPESVD QLQQLMMHDS AYFNTNNVAL NPTNVLEADP FDGHTNTMLN TTTDVLNKLL
     NDHYEIDNIL QPPDDALLVD QQQSSSEATG TSASKAVPMG PSHSNTHFSS NYLNEEYLML
     GDILLQSKPT SPSPSNTSAS EYNMLSPSYT QNIDFDNIHL SKRKVVQKLK DSRPFISLGF
     PKDSSLSLDN LNNMAHQTDN LLDNNVSSRG NNNTSNQKLQ SAIASKTSKT NPIINFATKY
     STEYVSPLST HQIYQTVSDI YSKDVLNYEY PNSYHALTHF LKTRFSGNNL PHEEKARKRQ
     NLLVILKLIA SYRPTFISAH KSLLKPQDLL FLEMSFQRCL IDYEKLSQLN SSPTIIWRRT
     GEIVSITDDL LSLLGYKLLD ILSKRTFIME IMYDDESIVK YFQLFKSVAV GNLHSSINTK
     VKLIKNGGAV PGGGTSNGKY NYNNNYNHNY SHNNNNNNNS NNSNNNGMST GAGNSGDGDG
     LENNVGTNSY IEFCSVWTVK RDLFDIPMLI IGQFLPILPA GDGVRMY
//