A5DRY5 (A5DRY5_LODEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinate synthase, mitochondrial EMBL EDK41943.1

Gene names

ORF Names:

LELG_00121 EMBL EDK41943.1

Organism

Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus) [Complete proteome]

Taxonomic identifier

379508 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Lodderomyces

Protein attributes

Sequence length	575 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU003693
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003693

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003693
Molecular function	Transferase RuleBase RU003693
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5DRY5 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 01A88E13104094DA	FASTA	575	62,879
	10 20 30 40 50 60 MESLIKVSMS VCPFVQSTSV QTLRQMSKSS GVLAQRARQC PYMASAIHQK ESAREYSQAS 70 80 90 100 110 120 KPRSATISQS STGSMATSPS TPYHFGKDKL VDAQVNLGSN ETSFDFQGFM NDDLAKKRVD 130 140 150 160 170 180 KSYRYFNNIN RLANEFPRAH RTKEEDKVTV WCSNDYLGMG KNEVTINEMK RVLDMYGSGA 190 200 210 220 230 240 GGTRNIAGHN THAIKLESEL AALHKHEAAL VFSSCFVAND AVLSLFGQKI KDLVIFSDAL 250 260 270 280 290 300 NHASMIQGIR NSRAKKHVFK HNDLADLEEK LAQYPKSIPK LIAFESVYSM CGSIAPIEAI 310 320 330 340 350 360 CDLADKYGAV TFLDEVHAVG MYGPHGAGVA EHLNFEAHLQ AGLSNPDVQT VMSRVDMVTG 370 380 390 400 410 420 TLGKAYGCVG GYITGKANMI DWFRSYAPGF IFTTTLPPAI MAGASASIRY QRATLQDRIA 430 440 450 460 470 480 QQKNTRYVKN NMNQLGLPVI PNPSHIVPVL VGNAADAKRA SDLLLEKHDI YVQAINFPTV 490 500 510 520 530 540 PIGEERLRIT PTPGHGKEIS NHLIEAVDSV FNELNLKRIN DWARQGGLCG VGQEDASNIE 550 560 570 HMWTDEQLAL TDADLNPNVV NPTIAPVGVS SGVSL

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed: 19465905] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11503 / CBS 2605 / IFO 1676 / JCM 1781 / NRRL YB-4239 and ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH981524 Genomic DNA. Translation: EDK41943.1.
RefSeq	XP_001527601.1. XM_001527551.1.
3D structure databases
ProteinModelPortal	A5DRY5.
ModBase	Search...
Protein-protein interaction databases
STRING	A5DRY5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5234848.
KEGG	lel:LELG_00121.
Phylogenomic databases
OMA	CPFLARM.
OrthoDB	EOG412QDQ.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5DRY5_LODEL

Accession

Primary (citable) accession number: A5DRY5

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	November 16, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)