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A5DNX9 (EIF3G_PICGU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit G
Short name=eIF3g
Alternative name(s):
Eukaryotic translation initiation factor 3 RNA-binding subunit
Short name=eIF-3 RNA-binding subunit
Translation initiation factor eIF3 p33 subunit homolog
Short name=eIF3 p33 homolog
Gene names
Name:TIF35
ORF Names:PGUG_04980
OrganismMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii) [Complete proteome]
Taxonomic identifier294746 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Meyerozyma ›

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. This subunit can bind 18S rRNA By similarity. HAMAP-Rule MF_03006

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the eIF-3 subunit G family.

Contains 1 RRM (RNA recognition motif) domain.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandRNA-binding
   Molecular functionInitiation factor
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionnucleotide binding

Inferred from electronic annotation. Source: InterPro

translation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 274274Eukaryotic translation initiation factor 3 subunit G HAMAP-Rule MF_03006
PRO_0000366893

Regions

Domain191 – 27080RRM

Amino acid modifications

Modified residue1461Phosphoserine By similarity
Modified residue1641Phosphoserine By similarity
Modified residue1711Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
A5DNX9 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: D530A9B3AAF553DC

FASTA27430,908
        10         20         30         40         50         60 
MATSVIKSWA DAEDEIPAAE VINNPDGTKT VINYRMNANG QKIRHIQKIR EVKVKEKVHP 

        70         80         90        100        110        120 
LIAMRKNWSK YGKEKDMPAG PDARTTQLGE VVELKLGTSW KEIEKEEEEQ KAEQTQQIVS 

       130        140        150        160        170        180 
NQRIKCRTCG GNHFTSKCPF KDTLISDSAN TSAAATPEPD TDASGKYVPP SLRKGAGAVR 

       190        200        210        220        230        240 
DMSGRDRDDS TTLKISQLNT FVDEDMLRNE LLKRFHPLQR VTIVRNRETG ESRGFAYVSF 

       250        260        270 
VTERQAEEAL NTLNGKGYHS LILHLEWPKK RKAN

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CH408160 Genomic DNA. Translation: EDK40882.1.
RefSeqXP_001483025.1. XM_001482975.1.

3D structure databases

ProteinModelPortalA5DNX9.
ModBaseSearch...

Protein-protein interaction databases

STRING4929.A5DNX9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5124807.
KEGGpgu:PGUG_04980.

Phylogenomic databases

eggNOGCOG0724.
KOK03248.
OrthoDBEOG4QJVX7.

Family and domain databases

Gene3D3.30.70.330. 1 hit.
HAMAPMF_03006. eIF3g.
InterProIPR024675. eIF3g_N.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR017334. Transl_init_eIF-3_G.
[Graphical view]
PANTHERPTHR10352. PTHR10352. 1 hit.
PfamPF12353. eIF3g. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view]
PIRSFPIRSF037949. Transl_init_eIF-3_RNA-bind. 1 hit.
SMARTSM00360. RRM. 1 hit.
[Graphical view]
PROSITEPS50102. RRM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3G_PICGU
AccessionPrimary (citable) accession number: A5DNX9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 12, 2007
Last modified: April 3, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Translation initiation factors

List of translation initiation factor entries

SIMILARITY comments

Index of protein domains and families

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