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A5DNX9

- EIF3G_PICGU

UniProt

A5DNX9 - EIF3G_PICGU

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Protein

Eukaryotic translation initiation factor 3 subunit G

Gene
TIF35, PGUG_04980
Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. This subunit can bind 18S rRNA By similarity.UniRule annotation

GO - Molecular functioni

  1. nucleotide binding Source: InterPro
  2. translation initiation factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. formation of translation preinitiation complex Source: UniProtKB-HAMAP
  2. regulation of translational initiation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 3 subunit G
Short name:
eIF3g
Alternative name(s):
Eukaryotic translation initiation factor 3 RNA-binding subunit
Short name:
eIF-3 RNA-binding subunit
Translation initiation factor eIF3 p33 subunit homolog
Short name:
eIF3 p33 homolog
Gene namesi
Name:TIF35
ORF Names:PGUG_04980
OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Taxonomic identifieri294746 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
ProteomesiUP000001997: Unassembled WGS sequence

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. eukaryotic 43S preinitiation complex Source: UniProtKB-HAMAP
  2. eukaryotic 48S preinitiation complex Source: UniProtKB-HAMAP
  3. eukaryotic translation initiation factor 3 complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 274274Eukaryotic translation initiation factor 3 subunit GUniRule annotationPRO_0000366893Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei146 – 1461Phosphoserine By similarity
Modified residuei164 – 1641Phosphoserine By similarity
Modified residuei171 – 1711Phosphoserine By similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Protein-protein interaction databases

STRINGi4929.A5DNX9.

Structurei

3D structure databases

ProteinModelPortaliA5DNX9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini191 – 27080RRMAdd
BLAST

Sequence similaritiesi

Belongs to the eIF-3 subunit G family.

Phylogenomic databases

eggNOGiCOG0724.
KOiK03248.
OrthoDBiEOG7J44J3.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
HAMAPiMF_03006. eIF3g.
InterProiIPR017334. eIF3_g.
IPR024675. eIF3g_N.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PANTHERiPTHR10352. PTHR10352. 1 hit.
PfamiPF12353. eIF3g. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view]
PIRSFiPIRSF037949. Transl_init_eIF-3_RNA-bind. 1 hit.
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5DNX9-1 [UniParc]FASTAAdd to Basket

« Hide

MATSVIKSWA DAEDEIPAAE VINNPDGTKT VINYRMNANG QKIRHIQKIR    50
EVKVKEKVHP LIAMRKNWSK YGKEKDMPAG PDARTTQLGE VVELKLGTSW 100
KEIEKEEEEQ KAEQTQQIVS NQRIKCRTCG GNHFTSKCPF KDTLISDSAN 150
TSAAATPEPD TDASGKYVPP SLRKGAGAVR DMSGRDRDDS TTLKISQLNT 200
FVDEDMLRNE LLKRFHPLQR VTIVRNRETG ESRGFAYVSF VTERQAEEAL 250
NTLNGKGYHS LILHLEWPKK RKAN 274
Length:274
Mass (Da):30,908
Last modified:June 12, 2007 - v1
Checksum:iD530A9B3AAF553DC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH408160 Genomic DNA. Translation: EDK40882.1.
RefSeqiXP_001483025.1. XM_001482975.1.

Genome annotation databases

GeneIDi5124807.
KEGGipgu:PGUG_04980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH408160 Genomic DNA. Translation: EDK40882.1 .
RefSeqi XP_001483025.1. XM_001482975.1.

3D structure databases

ProteinModelPortali A5DNX9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 4929.A5DNX9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5124807.
KEGGi pgu:PGUG_04980.

Phylogenomic databases

eggNOGi COG0724.
KOi K03248.
OrthoDBi EOG7J44J3.

Family and domain databases

Gene3Di 3.30.70.330. 1 hit.
HAMAPi MF_03006. eIF3g.
InterProi IPR017334. eIF3_g.
IPR024675. eIF3g_N.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view ]
PANTHERi PTHR10352. PTHR10352. 1 hit.
Pfami PF12353. eIF3g. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF037949. Transl_init_eIF-3_RNA-bind. 1 hit.
SMARTi SM00360. RRM. 1 hit.
[Graphical view ]
PROSITEi PS50102. RRM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324.

Entry informationi

Entry nameiEIF3G_PICGU
AccessioniPrimary (citable) accession number: A5DNX9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 12, 2007
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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