A5DLE2 (SRR1_PICGU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Stress response regulator protein 1

Gene names

Name:	SRR1
ORF Names:	PGUG_04093

Organism

Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii) [Complete proteome]

Taxonomic identifier

294746 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Meyerozyma › Meyerozyma guilliermondii

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for stress adaptation, morphogenesis and virulence By similarity.
Sequence similarities	Contains 1 response regulatory domain.

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	intracellular signal transduction Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Molecular_function	phosphorelay response regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	Stress response regulator protein 1		PRO_0000413392
Regions
	Domain	90 – 209	120	Response regulatory
Amino acid modifications
	Modified residue	142	1	4-aspartylphosphate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5DLE2 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: FE6BE643D8A9BEAB	FASTA	218	24,729
	10 20 30 40 50 60 MNSPDQIPFN TQLYTPPAQP ITSTDYFSKK GNAPKLAVDV DLEPRTVPSF SHRHTEVTKY 70 80 90 100 110 120 ISPVDKLSPD VETPAEVGPA NFIPNMSQYR FLLVDDNSIN LKILTKILLR LYPRAHIVEL 130 140 150 160 170 180 CDSTSVLAYL ASTPPFDCVF LDIEMPVVSG TELAYRIRQS PKLCRLPLIA VTTRTQEEDL 190 200 210 AQYKDVGIDW TFGKPFNYPY RVVLDVVDNV LRQRINEL

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH408159 Genomic DNA. Translation: EDK39995.1.
RefSeq	XP_001483364.1. XM_001483314.1.
3D structure databases
ProteinModelPortal	A5DLE2.
ModBase	Search...
Protein-protein interaction databases
STRING	4929.A5DLE2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5125429.
KEGG	pgu:PGUG_04093.
Phylogenomic databases
OrthoDB	EOG4HQHV0.
Family and domain databases
InterPro	IPR011006. CheY-like_superfamily. IPR001789. Sig_transdc_resp-reg_receiver. [Graphical view]
Pfam	PF00072. Response_reg. 1 hit. [Graphical view]
SMART	SM00448. REC. 1 hit. [Graphical view]
SUPFAM	SSF52172. CheY_like. 1 hit.
PROSITE	PS50110. RESPONSE_REGULATORY. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SRR1_PICGU

Accession

Primary (citable) accession number: A5DLE2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 19, 2011
Last sequence update:	June 12, 2007
Last modified:	April 3, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program