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Protein

DNA ligase

Gene

PGUG_03526

Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PGUG_03526Imported
OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)Imported
Taxonomic identifieri294746 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
ProteomesiUP000001997 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi294746.XP_001484145.1.

Structurei

3D structure databases

ProteinModelPortaliA5DJS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiA5DJS5.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5DJS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRISIRCFN PRQYIRLMPQ QQSIARFFGG SNVTKRKLDE KKDVKRIKKE
60 70 80 90 100
DINTLIDEKN GTPEDKSSPV ESGEPPQSPE KAASAPTTKT EASKLITMTD
110 120 130 140 150
NEAKKHTNET LGPKIPYAKL TEVFEKIEGE SSRLAITAIV SQFFQEILEQ
160 170 180 190 200
SSPDKLVKIV YLFINRLGPD YEPDLELGLG ETLLIKAISE CYGRAPAKIK
210 220 230 240 250
KDYHEVGDLG IVAQKSRSGQ PTMFRPTSLD VDTVFENLTK IAKFSGKDSQ
260 270 280 290 300
GKKIGMINKM LTACDLKSNE AKFLIRSLEG KLRIGLAEKT VLIALAQAFV
310 320 330 340 350
NHELSSSGKK INPEKLTSAE DIVREAFSRT PNYEVLIKKA AEFGVFNLLE
360 370 380 390 400
HCKLTPGIPL KPMLAKPTKS ISEVLDRFQG EDFTCEYKYD GERAQVHLLE
410 420 430 440 450
TGEVRIYSRN SEDMSQRYPD LISILKDFVK TQAEETKITS MVLDCEAVAW
460 470 480 490 500
DRVNNKILPF QVLSTRKRKD VDEKDIKVHI CLFAFDLLYY NGEPLITKSL
510 520 530 540 550
ADRREIMHKH IDTIEGKFQF ATAKNSSNLD ELQAFLDQSV KDACEGLMVK
560 570 580 590 600
MLHGPDSYYE PSKRSRNWLK LKKDYLAGVG DSLDLVVIGA YIGRGKRTGG
610 620 630 640 650
YGGFLLASYN QDTGEYETTC KIGTGFSEQD LADLHAKLSP TEIKQPKSYY
660 670 680 690 700
VYDTTNSNAV PDVWFEPTLV FEVLTADLSL SPIYKAAHHE YGKGISLRFP
710 720 730
RFLRVRDDKG IEDATSSTEV AEFYERQANM N
Length:731
Mass (Da):82,365
Last modified:June 12, 2007 - v1
Checksum:i18532B690F4343F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408158 Genomic DNA. Translation: EDK39428.1.
RefSeqiXP_001484145.1. XM_001484095.1.

Genome annotation databases

GeneIDi5125985.
KEGGipgu:PGUG_03526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408158 Genomic DNA. Translation: EDK39428.1.
RefSeqiXP_001484145.1. XM_001484095.1.

3D structure databases

ProteinModelPortaliA5DJS5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi294746.XP_001484145.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5125985.
KEGGipgu:PGUG_03526.

Phylogenomic databases

InParanoidiA5DJS5.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324Imported.

Entry informationi

Entry nameiA5DJS5_PICGU
AccessioniPrimary (citable) accession number: A5DJS5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: July 22, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.