A5DJS5 (A5DJS5_PICGU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

PGUG_03526 EMBL EDK39428.1

Organism

Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii) [Complete proteome] EMBL EDK39428.1

Taxonomic identifier

294746 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Meyerozyma › Meyerozyma guilliermondii

Protein attributes

Sequence length	731 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5DJS5 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 18532B690F4343F9	FASTA	731	82,365
	10 20 30 40 50 60 MLRISIRCFN PRQYIRLMPQ QQSIARFFGG SNVTKRKLDE KKDVKRIKKE DINTLIDEKN 70 80 90 100 110 120 GTPEDKSSPV ESGEPPQSPE KAASAPTTKT EASKLITMTD NEAKKHTNET LGPKIPYAKL 130 140 150 160 170 180 TEVFEKIEGE SSRLAITAIV SQFFQEILEQ SSPDKLVKIV YLFINRLGPD YEPDLELGLG 190 200 210 220 230 240 ETLLIKAISE CYGRAPAKIK KDYHEVGDLG IVAQKSRSGQ PTMFRPTSLD VDTVFENLTK 250 260 270 280 290 300 IAKFSGKDSQ GKKIGMINKM LTACDLKSNE AKFLIRSLEG KLRIGLAEKT VLIALAQAFV 310 320 330 340 350 360 NHELSSSGKK INPEKLTSAE DIVREAFSRT PNYEVLIKKA AEFGVFNLLE HCKLTPGIPL 370 380 390 400 410 420 KPMLAKPTKS ISEVLDRFQG EDFTCEYKYD GERAQVHLLE TGEVRIYSRN SEDMSQRYPD 430 440 450 460 470 480 LISILKDFVK TQAEETKITS MVLDCEAVAW DRVNNKILPF QVLSTRKRKD VDEKDIKVHI 490 500 510 520 530 540 CLFAFDLLYY NGEPLITKSL ADRREIMHKH IDTIEGKFQF ATAKNSSNLD ELQAFLDQSV 550 560 570 580 590 600 KDACEGLMVK MLHGPDSYYE PSKRSRNWLK LKKDYLAGVG DSLDLVVIGA YIGRGKRTGG 610 620 630 640 650 660 YGGFLLASYN QDTGEYETTC KIGTGFSEQD LADLHAKLSP TEIKQPKSYY VYDTTNSNAV 670 680 690 700 710 720 PDVWFEPTLV FEVLTADLSL SPIYKAAHHE YGKGISLRFP RFLRVRDDKG IEDATSSTEV 730 AEFYERQANM N

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH408158 Genomic DNA. Translation: EDK39428.1.
RefSeq	XP_001484145.1. XM_001484095.1.
3D structure databases
ProteinModelPortal	A5DJS5.
ModBase	Search...
Protein-protein interaction databases
STRING	4929.A5DJS5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5125985.
KEGG	pgu:PGUG_03526.
Phylogenomic databases
KO	K10747.
OrthoDB	EOG4RV60K.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5DJS5_PICGU

Accession

Primary (citable) accession number: A5DJS5

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	April 3, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)