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Protein

DNA ligase

Gene

PGUG_03526

Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PGUG_03526Imported
OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)Imported
Taxonomic identifieri294746 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
Proteomesi
  • UP000001997 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi4929.A5DJS5

Structurei

3D structure databases

ProteinModelPortaliA5DJS5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini473 – 610DNA_LIGASE_A3InterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiA5DJS5
KOiK10747
OMAiWIKYKRD
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

A5DJS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRISIRCFN PRQYIRLMPQ QQSIARFFGG SNVTKRKLDE KKDVKRIKKE
60 70 80 90 100
DINTLIDEKN GTPEDKSSPV ESGEPPQSPE KAASAPTTKT EASKLITMTD
110 120 130 140 150
NEAKKHTNET LGPKIPYAKL TEVFEKIEGE SSRLAITAIV SQFFQEILEQ
160 170 180 190 200
SSPDKLVKIV YLFINRLGPD YEPDLELGLG ETLLIKAISE CYGRAPAKIK
210 220 230 240 250
KDYHEVGDLG IVAQKSRSGQ PTMFRPTSLD VDTVFENLTK IAKFSGKDSQ
260 270 280 290 300
GKKIGMINKM LTACDLKSNE AKFLIRSLEG KLRIGLAEKT VLIALAQAFV
310 320 330 340 350
NHELSSSGKK INPEKLTSAE DIVREAFSRT PNYEVLIKKA AEFGVFNLLE
360 370 380 390 400
HCKLTPGIPL KPMLAKPTKS ISEVLDRFQG EDFTCEYKYD GERAQVHLLE
410 420 430 440 450
TGEVRIYSRN SEDMSQRYPD LISILKDFVK TQAEETKITS MVLDCEAVAW
460 470 480 490 500
DRVNNKILPF QVLSTRKRKD VDEKDIKVHI CLFAFDLLYY NGEPLITKSL
510 520 530 540 550
ADRREIMHKH IDTIEGKFQF ATAKNSSNLD ELQAFLDQSV KDACEGLMVK
560 570 580 590 600
MLHGPDSYYE PSKRSRNWLK LKKDYLAGVG DSLDLVVIGA YIGRGKRTGG
610 620 630 640 650
YGGFLLASYN QDTGEYETTC KIGTGFSEQD LADLHAKLSP TEIKQPKSYY
660 670 680 690 700
VYDTTNSNAV PDVWFEPTLV FEVLTADLSL SPIYKAAHHE YGKGISLRFP
710 720 730
RFLRVRDDKG IEDATSSTEV AEFYERQANM N
Length:731
Mass (Da):82,365
Last modified:June 12, 2007 - v1
Checksum:i18532B690F4343F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408158 Genomic DNA Translation: EDK39428.1
RefSeqiXP_001484145.1, XM_001484095.1

Genome annotation databases

EnsemblFungiiEDK39428; EDK39428; PGUG_03526
GeneIDi5125985
KEGGipgu:PGUG_03526

Similar proteinsi

Entry informationi

Entry nameiA5DJS5_PICGU
AccessioniPrimary (citable) accession number: A5DJS5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health