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Protein

DNA ligase

Gene

PGUG_02983

Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PGUG_02983Imported
OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)Imported
Taxonomic identifieri294746 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
Proteomesi
  • UP000001997 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi4929.A5DI82

Structurei

3D structure databases

ProteinModelPortaliA5DI82
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini381 – 509DNA_LIGASE_A3InterPro annotationAdd BLAST129
Domaini659 – 758BRCTInterPro annotationAdd BLAST100
Domaini822 – 928BRCTInterPro annotationAdd BLAST107

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0966 Eukaryota
COG1793 LUCA
InParanoidiA5DI82
KOiK10777
OMAiHMCPSTK
OrthoDBiEOG092C18KW

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
3.40.50.10190, 2 hits
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR029710 LIG4
IPR012340 NA-bd_OB-fold
PANTHERiPTHR10459:SF7 PTHR10459:SF7, 1 hit
PfamiView protein in Pfam
PF16589 BRCT_2, 2 hits
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 2 hits
SUPFAMiSSF50249 SSF50249, 1 hit
SSF52113 SSF52113, 2 hits
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 2 hits
PS00697 DNA_LIGASE_A1, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

A5DI82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYLDNVEAP KNHLDDADFD FLVSQLFTKV DGVSHQNLGE FPTISSKKVY
60 70 80 90 100
VIEQFIKQWK TFIGPDIMPA APLIFPNKAK RLYYIRDTTL ARLVVKMLKI
110 120 130 140 150
SPKSQDYDKL FKWKKHYHEY KHHHRRDTRN LKSLPFIIAQ IYSERRDPDK
160 170 180 190 200
IVKPTIKISE VNKVLETLTT DEASKSAQQV AILEPVVEKL TIEQLRWFFT
210 220 230 240 250
ILLKISTLGS FETAFFERWH PDAPRLYGLC NNLSKVFWLL TDPEVRLTDD
260 270 280 290 300
QLTIQPFYPF LPQLSQKVNI SYEKLCARMN NAFYIEEKMD GDRMILHFQD
310 320 330 340 350
SRFKFFSRRT KDYTLLYGAS FQIGSLTKYL TDAFHPRVKS IVLDGEMVAW
360 370 380 390 400
DFKRKVILPF GTLKTSAVQE AVRQFTTTDV FEEQSAWPLF IVFDVLHVNG
410 420 430 440 450
KNLTNHKLSY RKQLLRSLIN EIPHKFELLP LMKGSDPDDI KLAIKNVISD
460 470 480 490 500
RGEGLVIKNV DSKYHVAQRD NSWVKVKPEY LEQFGENLDL VIIGLIPAVK
510 520 530 540 550
NSYMCGLRDK ENGNVFKSFC TVANGFTEGE FDRLERLTAG KWNNLKTNPP
560 570 580 590 600
PTDLIQFGRK KPDFWINPND SVALEIKARS IDVSLEETYA VGTTLHNLYC
610 620 630 640 650
RRIRDDKLIE DCVTLQEYRE MKLKYSSDFN KSQTILQGRK RKANSFLLEQ
660 670 680 690 700
ASKQVKTEVT SNLFSNFQFL ILSDCKKSRD NERLSVEDLS RIVKSHGGML
710 720 730 740 750
IRSHKLAKEP DRQTIVISEV AIPSTEAIVN YGLDILKSVW VFNCIESNAI
760 770 780 790 800
VPLEPSMIFR TRSVDLLKNS SARLDVYGDS FTQRVDLPIV EFCRRIENPQ
810 820 830 840 850
LTDNDIKCAK EEFLHELGDN PPLAFLFNDV KFLIVAAHNW AKDGLRRKVE
860 870 880 890 900
RYGGQISETL GDCSFVVVAN EEGDETLAAR IDVISHDIAD SVSFSNSSNL
910 920 930
PIPSIVKSSF IDSCIEHRVL VDAADFSIGR KSKMRKN
Length:937
Mass (Da):107,853
Last modified:July 22, 2008 - v2
Checksum:i11DEFA0C58280A80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408157 Genomic DNA Translation: EDK38885.2
RefSeqiXP_001485254.1, XM_001485204.1

Genome annotation databases

EnsemblFungiiEDK38885; EDK38885; PGUG_02983
GeneIDi5126991
KEGGipgu:PGUG_02983

Similar proteinsi

Entry informationi

Entry nameiA5DI82_PICGU
AccessioniPrimary (citable) accession number: A5DI82
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: July 22, 2008
Last modified: March 28, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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