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A5DG64

- A5DG64_PICGU

UniProt

A5DG64 - A5DG64_PICGU

Protein

Histone deacetylase

Gene

PGUG_02265

Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 2 (22 Jul 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    ORF Names:PGUG_02265Imported
    OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)Imported
    Taxonomic identifieri294746 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
    ProteomesiUP000001997: Unassembled WGS sequence

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi4929.A5DG64.

    Structurei

    3D structure databases

    ProteinModelPortaliA5DG64.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    KOiK06067.
    OrthoDBiEOG78M0B2.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    A5DG64-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYSQLPFDEI KVDESQKKRV AYFYDADVGN YAYGAGHPMK PHRIRMAHSL    50
    IMNYGLYKKM EIYRAKPATK QEMCQFHTDE YIDFLSRVTP DNLDMFAKEQ 100
    IKFNVGDDCP VFDGLFEYCG ISGGGSMEGA ARLNRGKCDI AINYAGGLHH 150
    AKKSEASGFC YLNDIVLGII ELLRYHPRVL YIDIDVHHGD GVEEAFYTTD 200
    RVMTASFHKY GEFFPGTGEL RDVGIGKGKY HAINVPLRDG IDDSSYKSIF 250
    EPVIQKIMEW YQPSCVVLQC GGDSLSGDRL GCFNLSMAGH ANCINFVKSF 300
    NIPMMVVGGG GYTMRNVART WAFEAGLLNN VVLPSELPYN EYYEYYGPDY 350
    KLDVRPSNMY NANSPEFLNK ILTYIISNFD NTKHAPSVQM NYTPHDPEDL 400
    GDVDEDTPEA YDTKGGSQQA RDEMVVAPGE HYDDREPVRN IDEVTQTNGE 450
    KADQNGNPNG SNGSQNGNSN HGNQNETGNQ ETDKLSLTDE EMKAIEELNQ 500
    EADKKED 507
    Length:507
    Mass (Da):56,956
    Last modified:July 22, 2008 - v2
    Checksum:i2E8A106C52023A90
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408156 Genomic DNA. Translation: EDK38167.2.
    RefSeqiXP_001486594.1. XM_001486544.1.

    Genome annotation databases

    GeneIDi5128086.
    KEGGipgu:PGUG_02265.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408156 Genomic DNA. Translation: EDK38167.2 .
    RefSeqi XP_001486594.1. XM_001486544.1.

    3D structure databases

    ProteinModelPortali A5DG64.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4929.A5DG64.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5128086.
    KEGGi pgu:PGUG_02265.

    Phylogenomic databases

    KOi K06067.
    OrthoDBi EOG78M0B2.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324Imported.

    Entry informationi

    Entry nameiA5DG64_PICGU
    AccessioniPrimary (citable) accession number: A5DG64
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 12, 2007
    Last sequence update: July 22, 2008
    Last modified: October 1, 2014
    This is version 43 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3