A5DFW2 (A5DFW2_PICGU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Uridine kinase RuleBase RU003825
EC=2.7.1.48 RuleBase RU003825

Gene names

ORF Names:

PGUG_02163 EMBL EDK38065.2

Organism

Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii) [Complete proteome] EMBL EDK38065.2

Taxonomic identifier

294746 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Meyerozyma › Meyerozyma guilliermondii

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + cytidine = ADP + CMP. RuleBase RU003825 ATP + uridine = ADP + UMP. RuleBase RU003825
Pathway	Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. RuleBase RU003825 Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. RuleBase RU003825
Sequence similarities	Belongs to the uridine kinase family. RuleBase RU003824

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003528 Nucleotide-binding
Molecular function	Kinase RuleBase RU003528 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	CTP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway UMP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro uridine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5DFW2 [UniParc]. Last modified July 22, 2008. Version 2. Checksum: 869A7C1FB3CBB640	FASTA	490	55,606
	10 20 30 40 50 60 MASKIPSRII PSKNDSFFSP GPEEREKGAY IPPWTEPYII GVAGNSGSGK TSVSQRIIQE 70 80 90 100 110 120 LNQPWTVILS FDNFYKDLNP EERERAFKNQ YDFDEPASFD LDSLVETVKS LRAGKKTQIP 130 140 150 160 170 180 VYSFKNHART KKVTTIYGAN VIIIEGIMAL YDSRLTDLMD LKVYVDTDLD VCLARRLTRD 190 200 210 220 230 240 TLFRGRDPSG VMDQWEGFVK PNAVRYVNPT MNQADIIIPR GLENTKAIDL MIQHVQKQLG 250 260 270 280 290 300 KKSVLHLQRL TELGIKQEFN LEKHPNVKLI PNNNHTLGIN SILFNVETER TDFIFYFERI 310 320 330 340 350 360 SILIIEAALD DLTAYEPKEV TTATNYKFNG IKHIGEVVAV NIIRSGDCFM TAIKKTFPEI 370 380 390 400 410 420 SIGKLLIQSD SLTGEPQLHT ESLPKDLYKI SNGRVLLCDA QVISGAAAIM AIQVLIDHQV 430 440 450 460 470 480 PQENIILCTY LCTELGMRRI LRVFPGINMV IGKLSELDMG ETPKDYNPEG FKDIHRPFRK 490 RWIDKVYFGT

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH408156 Genomic DNA. Translation: EDK38065.2.
RefSeq	XP_001486492.1. XM_001486442.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	4929.A5DFW2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5128345.
KEGG	pgu:PGUG_02163.
Phylogenomic databases
KO	K00876.
OrthoDB	EOG4NZZ30.
Enzyme and pathway databases
UniPathway	UPA00574; UER00637. UPA00579; UER00640.
Family and domain databases
InterPro	IPR006083. PRK/URK. IPR000764. Uridine_kinase. [Graphical view]
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PRINTS	PR00988. URIDINKINASE.
TIGRFAMs	TIGR00235. udk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5DFW2_PICGU

Accession

Primary (citable) accession number: A5DFW2

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	July 22, 2008
Last modified:	April 3, 2013
This is version 44 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)