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A5DF43

- ERT1_PICGU

UniProt

A5DF43 - ERT1_PICGU

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Protein

Transcription activator of gluconeogenesis ERT1

Gene

ERT1

Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi63 – 9129Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. signal transducer activity Source: InterPro
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis ERT1
Gene namesi
Name:ERT1
ORF Names:PGUG_01894
OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Taxonomic identifieri294746 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
ProteomesiUP000001997: Unassembled WGS sequence

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 468468Transcription activator of gluconeogenesis ERT1PRO_0000406465Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi4929.A5DF43.

Structurei

3D structure databases

ProteinModelPortaliA5DF43.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini349 – 42274PASAdd
BLAST

Sequence similaritiesi

Belongs to the ERT1/acuK family.Curated
Contains 1 PAS (PER-ARNT-SIM) domain.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG39365.
InParanoidiA5DF43.
OrthoDBiEOG70KGZB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR000014. PAS.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5DF43-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAPAEAGQR PVSTPVFRFK LNKVSAYGAL NSLIVFRIIF LLKNPLFLMF
60 70 80 90 100
TNKQKRKKTI RACTHCHRAH LLCDENRPCA RCVQKGLQAT CQDAPRKRKK
110 120 130 140 150
YLLDVPPDSM QKQRYQSPEI KPEYPMNTLL PLPGQQIQRK SNFLSSAADM
160 170 180 190 200
EYSTLSNILS ENVHPFPNPS TSNEGTPNSI TLSPALSPGT GGRTSTTYTA
210 220 230 240 250
PTDIACDNAL NQYVLGPTTT GISLYPDVVM AIETLKNTHP SVIHERNTRS
260 270 280 290 300
TVSYAMGFMP DGNPHVSLPG GDYASVYAEP EDIYAKVRKP YSYTPGYHAL
310 320 330 340 350
IAYLRSRFPK QMLVKMAESM AAYRPSFIAC TNALKEDDLI FMEQCFQRTL
360 370 380 390 400
LTYDNFIKLS GTPTIVWRRT GEIAYVGDEF CVLTGWPKAE LITQKKRLIV
410 420 430 440 450
ELLDDKSVVE YFELFSKIAF GDFLGATMTE CTLLTSKPDV KIRTSCIWTL
460
KRDVFGIPMM IIGNFLPI
Length:468
Mass (Da):52,526
Last modified:July 22, 2008 - v2
Checksum:i0127120CDBC7966B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408156 Genomic DNA. Translation: EDK37796.2.
RefSeqiXP_001486223.1. XM_001486173.1.

Genome annotation databases

GeneIDi5128027.
KEGGipgu:PGUG_01894.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408156 Genomic DNA. Translation: EDK37796.2 .
RefSeqi XP_001486223.1. XM_001486173.1.

3D structure databases

ProteinModelPortali A5DF43.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 4929.A5DF43.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5128027.
KEGGi pgu:PGUG_01894.

Phylogenomic databases

eggNOGi NOG39365.
InParanoidi A5DF43.
OrthoDBi EOG70KGZB.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR000014. PAS.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
Pfami PF00172. Zn_clus. 1 hit.
[Graphical view ]
SMARTi SM00066. GAL4. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324.

Entry informationi

Entry nameiERT1_PICGU
AccessioniPrimary (citable) accession number: A5DF43
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: July 22, 2008
Last modified: October 29, 2014
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3