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Protein

Glutamate decarboxylase

Gene

PGUG_01858

Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:PGUG_01858Imported
OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)Imported
Taxonomic identifieri294746 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
ProteomesiUP000001997: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi4929.A5DF07.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

InParanoidiA5DF07.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

A5DF07-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLSKHFDVE EITHKLLNRT PKTTLSKDQH FLSAYDSNQV IPKFSIPENS
60 70 80 90 100
TDAELVYKYL SEELTLDGIP TLNLASFVTT TINDFPKRLA VENLTKNLAD
110 120 130 140 150
NDEYPSLIEF QNRCISILSN LWHAPTTPHP ETGVSVPTTI GAATTGSSEA
160 170 180 190 200
IMLGGLALKK SWQLRQKAAG KSTENPNIIM ASCAQVALEK FARYFDVEDR
210 220 230 240 250
IVPISKESRH VIDVSKIKEN IDENTIGIFV ILGSTFNGAF EPVEQIAKLL
260 270 280 290 300
DEVEKEKGLD IKIHVDGASG AFVAPFLFPN LKWDFAVDRV VSINTSGHKF
310 320 330 340 350
GLTSAGLGWV IWRDAKQLPE NLRFKLDYLG GVEETFGLNF SRPGFQVVHQ
360 370 380 390 400
YYNLLHLGRD GYTKIFESCQ QNARLLANVL EKSEYYDVVS EIHKKVDTKR
410 420 430 440 450
QDELYTLKGT RSENEGYEPG LPVIAFKLKD EIRKKYPELP QSIISLLLRN
460 470 480 490 500
KGFIVPNYHF PANEQNVEIL RVVVKESLSL NLLDKLMTDI IESTELLLNA
510 520 530 540 550
CTTAREIVKH HGSEKEQHAL IYEILLSIAS GGVEDVKAAQ HAAYDKEGTG
560
HRKHKKSYRG AC
Length:562
Mass (Da):63,060
Last modified:July 22, 2008 - v2
Checksum:i665EF91A6D27C844
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408156 Genomic DNA. Translation: EDK37760.2.
RefSeqiXP_001486187.1. XM_001486137.1.

Genome annotation databases

GeneIDi5128177.
KEGGipgu:PGUG_01858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408156 Genomic DNA. Translation: EDK37760.2.
RefSeqiXP_001486187.1. XM_001486137.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4929.A5DF07.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5128177.
KEGGipgu:PGUG_01858.

Phylogenomic databases

InParanoidiA5DF07.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324Imported.

Entry informationi

Entry nameiA5DF07_PICGU
AccessioniPrimary (citable) accession number: A5DF07
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: July 22, 2008
Last modified: February 4, 2015
This is version 42 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.