A5DEC2 (A5DEC2_PICGU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL EDK37525.2

Gene names

ORF Names:

PGUG_01623 EMBL EDK37525.2

Organism

Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii) [Complete proteome] EMBL EDK37525.2

Taxonomic identifier

294746 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Meyerozyma › Meyerozyma guilliermondii

Protein attributes

Sequence length	1455 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 N-terminal Ras-GEF domain. SAAS SAAS023578 Contains 1 Ras-GEF domain. SAAS SAAS023578

Ontologies

Keywords
Molecular function	Guanine-nucleotide releasing factor SAAS SAAS023578
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5DEC2 [UniParc]. Last modified July 22, 2008. Version 2. Checksum: A1F3C3EC649D4331	FASTA	1,455	164,166
	10 20 30 40 50 60 MPVHYSTSSS VYSPVESNFA FRRDELEQLN EDADEEYTNE QRQMNTEPST STFQTYVTAH 70 80 90 100 110 120 SGSEQSENSL AVPGASAGVY DTTPKLDNVP DFVNDETPII GNDGFFQNGT GPSRSSLLPH 130 140 150 160 170 180 QELHSRFKRL SVTLQSSSNG TSGDSYLFKN SFQQNVDRVN KDNNQLPYDN RTSAYYKRID 190 200 210 220 230 240 EPYGPDSSFD DDTQIQNDAE SSVARDRSSV ISTSSFSRSS ASSSRASSIR NYVTNKERAR 250 260 270 280 290 300 LAQDTETVTS GTDKTISNSS STNFNFNQDA SFVNFRGSRV SPTKPKAGST LEDVPIRRDL 310 320 330 340 350 360 VYKFDQENGS KNELSEKEKN DLAIHSAAPS LVGDSYGDSS LDPRSADASH LDESSTAETT 370 380 390 400 410 420 VDSIPNSMSS KIQVDEENLA SLFIRAIHPF DSSTLQSESD ASICLSFDKG DLAFVHTIDE 430 440 450 460 470 480 SGWGEVTLVE SLQRGWIPMN YFTIGVEEDL DGAEPFDDDD IGAIPNSIYL KPLFHSCGKF 490 500 510 520 530 540 LTNPLSHKNR HGKYTFSIRV INMIRDGVRL LLQETDCLSR ANEIVTKRPV VRKTRKSLLA 550 560 570 580 590 600 DWYNLMLKAN DFKGTSNFNK IEVLTLMVYQ VIRKATAFLQ VWSIESRQIV KRDTERALQS 610 620 630 640 650 660 DMNNHPLLPS PPQAKQRVTE INGLLYSYLG LIIGRLDLVE HNPVGCDMLE VLTHQIILLL 670 680 690 700 710 720 RELLFISKTG SDFSAEKPAE LDDSLDSLLS LVSDLVTDVK ALVSKTLNET EEDKNVYLSK 730 740 750 760 770 780 RANKSAGPKD YHYTAEGGAL IQIAAKMIKS ISGTVSAIRK LFEVTGDFKL NAERSYPDYA 790 800 810 820 830 840 KMKIDPEEFV KKCTIGMVQY QDLTKKQMKE YMPAKKQASN RFSMMRRGQT GALDITPGGL 850 860 870 880 890 900 SMLHDVMPNE NGKFGDDDAF KPFTNQSDTV KHNINDELLV DSNGNLLGAS FKGLVYTLTN 910 920 930 940 950 960 EDSPPEYFFV STFFICFRTF TNGIDLIEEL ITRFELGNNS QNVDINYEIK LKNRRRLIVK 970 980 990 1000 1010 1020 MFQLWLESYW NHEADSPLLT TFINFFNEGV ANYLPLDAMK LLEVAAKLSS KPLIENQGKS 1030 1040 1050 1060 1070 1080 RKAKPAKQLI TRSITVTRMN RKNATERTFV DSTLSSRYSM VDGYELSKIN TNSSTSSSLK 1090 1100 1110 1120 1130 1140 SMTLPMPLGV GNQTSSANSL LTKNQLITIE NVNLTYRAIL GESWCSEKFI STKEFIPLPL 1150 1160 1170 1180 1190 1200 GIMLDNWYKI CDQSWVLSNY RPNLLDFNGL EIAKQLTLVE SYIFCSIKPE ELLNENYTSK 1210 1220 1230 1240 1250 1260 RAHLNLAPNV RKSVLFTNSL SSYVLESILQ PKINIKMRVN MVKTWLKVAI SCLYLRNFNS 1270 1280 1290 1300 1310 1320 LAAIITALQS HLVTRLDRIW VELSDKYTEL YEYLSGIVHP NKNYNVYRTK LRNFLVANDY 1330 1340 1350 1360 1370 1380 NIPIVPYFQL FLQDLTFVMD GNPNFRKANT FLNQKLINID KYLKVTRIIA DIESLQTPYG 1390 1400 1410 1420 1430 1440 SQAISKEVSR NSFFGGNGKP QELEDYNIVA SPHLQELLLL EIWKVCQLNR KEDDRAWKLS 1450 CLIQPREGQT VNNVL

References

[1]

"Evolution of pathogenicity and sexual reproduction in eight Candida genomes." Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J. , Harris D., Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A. Nature 459:657-662(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH408156 Genomic DNA. Translation: EDK37525.2.
RefSeq	XP_001485952.1. XM_001485902.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5128542.
KEGG	pgu:PGUG_01623.
Phylogenomic databases
OrthoDB	EOG4DNJCG.
Family and domain databases
Gene3D	1.10.840.10. 1 hit.
InterPro	IPR000651. Ras-like_Gua-exchang_fac_N. IPR008937. Ras_GEF. IPR023578. Ras_GEF_dom. IPR001895. RasGRF_CDC25. IPR001452. SH3_domain. [Graphical view]
PANTHER	PTHR23113. PTHR23113. 1 hit.
Pfam	PF00617. RasGEF. 1 hit. PF00618. RasGEF_N. 1 hit. [Graphical view]
SMART	SM00147. RasGEF. 1 hit. SM00229. RasGEFN. 1 hit. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF48366. Ras_GEF. 1 hit. SSF50044. SH3. 1 hit.
PROSITE	PS50009. RASGEF_CAT. 1 hit. PS50212. RASGEF_NTER. 1 hit. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5DEC2_PICGU

Accession

Primary (citable) accession number: A5DEC2

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	July 22, 2008
Last modified:	March 6, 2013
This is version 38 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)