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A5DE24

- OCA1_PICGU

UniProt

A5DE24 - OCA1_PICGU

Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 2 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei116 – 1161Phosphocysteine intermediateBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    Stress response

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
    Gene namesi
    Name:OCA1
    ORF Names:PGUG_01525
    OrganismiMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
    Taxonomic identifieri294746 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeMeyerozyma
    ProteomesiUP000001997: Unassembled WGS sequence

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 185185Putative tyrosine-protein phosphatase OCA1PRO_0000333393Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi4929.A5DE24.

    Structurei

    3D structure databases

    ProteinModelPortaliA5DE24.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG2365.
    KOiK18043.
    OrthoDBiEOG7Z0K6V.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view]
    PfamiPF03162. Y_phosphatase2. 1 hit.
    [Graphical view]
    PRINTSiPR01911. PFDSPHPHTASE.
    SUPFAMiSSF52799. SSF52799. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A5DE24-1 [UniParc]FASTAAdd to Basket

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    MSRKVVQPPS LRIIPPLNFC PVEKQLYRSG QPSIINQSFL QDLNLKTIIW    50
    LASEEPQEEF LDYCSMNSIN IEFVGMINDD YSYQNVNPWD SLNETTIKKA 100
    LELICDRNNY PMLVCCGMGR HRTGTVIGCL RRLQGWNLAS VSEEYRRFTG 150
    ARGGRILVEL LIEGFDISTV EIGSGKGSSM ARKKR 185
    Length:185
    Mass (Da):21,040
    Last modified:February 10, 2009 - v2
    Checksum:i382D81D40AEF31C0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408156 Genomic DNA. Translation: EDK37427.2.
    RefSeqiXP_001485854.1. XM_001485804.1.

    Genome annotation databases

    GeneIDi5128470.
    KEGGipgu:PGUG_01525.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408156 Genomic DNA. Translation: EDK37427.2 .
    RefSeqi XP_001485854.1. XM_001485804.1.

    3D structure databases

    ProteinModelPortali A5DE24.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4929.A5DE24.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5128470.
    KEGGi pgu:PGUG_01525.

    Phylogenomic databases

    eggNOGi COG2365.
    KOi K18043.
    OrthoDBi EOG7Z0K6V.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view ]
    Pfami PF03162. Y_phosphatase2. 1 hit.
    [Graphical view ]
    PRINTSi PR01911. PFDSPHPHTASE.
    SUPFAMi SSF52799. SSF52799. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324.

    Entry informationi

    Entry nameiOCA1_PICGU
    AccessioniPrimary (citable) accession number: A5DE24
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3