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Protein
Submitted name:

WNK1 protein

Gene

WNK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
WNK1 proteinImported
Gene namesi
Name:WNK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiA5D8Z4.
PeptideAtlasiA5D8Z4.
PRIDEiA5D8Z4.

Expressioni

Gene expression databases

GenevisibleiA5D8Z4. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000313059.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0584. Eukaryota.
ENOG410XQWZ. LUCA.
HOVERGENiHBG048577.

Sequencei

Sequence statusi: Fragment.

A5D8Z4-1 [UniParc]FASTAAdd to basket

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        10         20         30         40         50
GAAEKQSKKK KKQEESSLKQ QVEQSSASQT GIKQLPSAST GIPTASTTSA
60 70 80 90 100
SVSTQVEPEE PEADQHQQLQ YQQPSISVLS DGTVDSGQGS SVFTESRVSS
110 120 130 140 150
QQTVSYGSQH EQAHSTGTVP GHIPSTVQAQ SQPHGVYPPS SVQQGIQQTA
160 170 180 190 200
PPQQTVQYSL SQTSTSSEAT TAQPVSQPQA PQVLPQVSAG KQSTQGVSQV
210 220 230 240 250
APAEPVAVAQ PQATQPTTLA SSVDSAHSDV ASGMSDGNEN VPSSSGRHEG
260 270 280 290 300
RTTKRHYRKS VRSRSRHEKT SRPKLRILNV SNKGDRVVEC QLETHNRKMV
310 320 330 340 350
TFKFDLDGDN PEEIATIMVN NDFILAIERE SFVDQVREII EKADEMLSED
360 370 380 390 400
VSVEPEGDQG LESLQGKDDY GFSGSQKLEG EFKQPIPASS MPQQIGIPTS
410 420 430 440 450
SLTQVVHSAG RRFIVSPVPE SRLRESKVFP SEITDTVAAS TAQSPGMNLS
460 470 480 490 500
HSASSLSLQQ AFSELRRAQM TEGPNTAPPN FSHTGPTFPV VPPFLSSIAG
510 520 530 540 550
VPTTAAATAP VPATSSPPND ISTSVIQSEV TVPTEEGIAG VATSTGVVTS
560 570 580 590 600
GGLPIPPVSE SPVLSSVVSS ITIPAVVSIS TTSPSLQVPT STSEIVVSST
610 620 630 640 650
ALYPSVTVSA TSASAGGSTA TPGPKPPAVV SQQAAGSTTV GATLTSVSTT
660 670 680 690 700
TSFPSTASQL SIQLSSSTST PTLAETVVVS AHSLDKTSHS STTGLAFSLS
710 720 730 740 750
APSSSSSPGA GVSSYISQPG GLHPLVIPSV IASTPILPQA AGPTSTPLLP
760 770 780 790 800
QVPSIPPLVQ PVANVPAVQQ TLIHSQPQPA LLPNQPHTHC PEVDSDTQPK
810 820 830 840 850
APGIDDIKTL EEKLRSLFSE HSSSGAQHAS VSLETSLVIE STVTPGIPTT
860 870 880 890 900
AVAPSKLLTS TTSTCLPPTN LPLGTVALPV TPVVTPGQVS TPVSTTTSGV
910 920 930 940 950
KPGTAPSKPP LTKAPVLPVG TELPAGTLPS EQLPPFPGPS LTQSQQPLED
960 970 980 990 1000
LDAQLRRTLS PEMITVTSAV GPVSMAAPTA ITEAGTQPQK GVSQVKEGPV
1010 1020 1030 1040 1050
LATSSGAGVF KMGRFQVSVA ADGAQKEGKN KSEDAKSVHF ESSTSESSVL
1060 1070 1080 1090 1100
SSSSPESTLV KPEPNGITIP GISSDVPESA HKTTASEAKS DTGQPTKVGR
1110 1120 1130 1140 1150
FQVTTTANKV GRFSVSKTED KITDTKKEGP VASPPFMDLE QAVLPAVIPK
1160 1170 1180 1190 1200
KEKPELSEPS HLNGPSSDPE AAFLSRDVDD GSGSPHSPHQ LSSKSLPSQN
1210 1220 1230 1240 1250
LSQSLSNSFN SSYMSSDNES DIEDEDLKLE LRRLRDKHLK EIQDLQSRQK
1260 1270 1280 1290 1300
HEIESLYTKL GKVPPAVIIP PAAPLSGRRR RPTKSKGSKS SRSSSLGNKS
1310 1320 1330 1340 1350
PQLSGNLSGQ SAASVLHPQQ TLHPPGNIPE SGQNQLLQPL KPSPSSDNLY
1360 1370 1380 1390 1400
SAFTSDGAIS VPSLSAPGQG TSSTNTVGAT VNSQAAQAQP PAMTSSRKGT
1410 1420 1430 1440 1450
FTDDLHKLVD NWARDAMNLS GRRGSKGHMN YEGPGMARKF SAPGQLCISM
1460 1470 1480 1490 1500
TSNLGGSAPI SAASATSLGH FTKSMCPPQQ YGFPATPFGA QWSGTGGPAP
1510 1520 1530
QPLGQFQPVG TASLQNFNIS NLQKSISNPP GSNLRTT
Length:1,537
Mass (Da):159,519
Last modified:June 12, 2007 - v1
Checksum:iE87300B229B53FE2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC141881 mRNA. Translation: AAI41882.1.
RefSeqiNP_055638.2. NM_014823.2.
NP_061852.3. NM_018979.3.
UniGeneiHs.744906.

Genome annotation databases

GeneIDi65125.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC141881 mRNA. Translation: AAI41882.1.
RefSeqiNP_055638.2. NM_014823.2.
NP_061852.3. NM_018979.3.
UniGeneiHs.744906.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000313059.

Proteomic databases

PaxDbiA5D8Z4.
PeptideAtlasiA5D8Z4.
PRIDEiA5D8Z4.

Protocols and materials databases

DNASUi65125.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi65125.

Organism-specific databases

CTDi65125.

Phylogenomic databases

eggNOGiKOG0584. Eukaryota.
ENOG410XQWZ. LUCA.
HOVERGENiHBG048577.

Miscellaneous databases

ChiTaRSiWNK1. human.
GenomeRNAii65125.

Gene expression databases

GenevisibleiA5D8Z4. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiA5D8Z4_HUMAN
AccessioniPrimary (citable) accession number: A5D8Z4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: July 6, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.