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A5D8S8 (HEXIM_DANRE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Protein HEXIM
Gene names
Name:hexim
ORF Names:zgc:162976
OrganismDanio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the HEXIM family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 319319Protein HEXIM
PRO_0000305269

Regions

Coiled coil240 – 30667 Potential

Sequences

Sequence LengthMass (Da)Tools
A5D8S8 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 762A2AE3A8B1FB09

FASTA31936,219
        10         20         30         40         50         60 
MELIKEETAP EDDSRGRQRD CRTSVVSSKQ VQRNQLEICP GLVSGDVHPM CRDRSDPEPR 

        70         80         90        100        110        120 
TGDAASDDGF PADKTSSKRD SECAAVNTDG VSDGRQGKKK HRRRPSKKKR RWKPYFKLTW 

       130        140        150        160        170        180 
EEKKELDERE TARASRVRAE MFAKGLPVAP YNTTQFLMEE HDREEPDLNT ELGGRKSGAI 

       190        200        210        220        230        240 
RSEDTASEDE NFEAEEDDEE EGGGGSDGMG RPGQAGGEFL QKDFSETYEK YHVEALQNMS 

       250        260        270        280        290        300 
KQELVREYLE LEKCMSRLEE ENNWLRHVRR NPESPADGTG SQRVRELEVE VEKLRAENNE 

       310 
LLLKTPASNE PGLNQSQPS 

« Hide

References

[1]NIH - Zebrafish Gene Collection (ZGC) project
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Ovary.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC141797 mRNA. Translation: AAI41798.1.
IPIIPI00631045.
RefSeqNP_001091859.1. NM_001098389.1.
UniGeneDr.80032.

3D structure databases

ProteinModelPortalA5D8S8.
SMRA5D8S8. Positions 216-302.
ModBaseSearch...

Protein-protein interaction databases

STRING7955.ENSDARP00000053002.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID562319.
KEGGdre:562319.

Organism-specific databases

CTD10614.
ZFINZDB-GENE-030131-4637. hexim1.

Phylogenomic databases

eggNOGNOG72325.
HOGENOMHOG000060338.
HOVERGENHBG053249.
InParanoidA5D8S8.
KOK15189.
OrthoDBEOG40GCRK.

Family and domain databases

InterProIPR024872. HEXIM.
[Graphical view]
PANTHERPTHR13469. PTHR13469. 1 hit.
PRINTSPR02094. HEXIMFAMILY.
ProtoNetSearch...

Other

NextBio20884347.

Entry information

Entry nameHEXIM_DANRE
AccessionPrimary (citable) accession number: A5D8S8
Entry history
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: June 12, 2007
Last modified: May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families