A5D4H9 (A5D4H9_PELTS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Name:	Ald EMBL BAF58839.1
Ordered Locus Names:	PTH_0658

Organism

Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) [Complete proteome] [HAMAP]

Taxonomic identifier

370438 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Pelotomaculum

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5D4H9 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 11E5568035262B51	FASTA	389	41,589
	10 20 30 40 50 60 MIIGVPKEIK PYEDRVAVTP AGVLALTAEG HKVLIEAGAG LGSGITDEAY AAAGAVLVDG 70 80 90 100 110 120 PAEVFGHADI IMKVKEPLPQ EYNLLREDQI LFAYLHLASE PELTEVLLEK KVVAVAYETI 130 140 150 160 170 180 QLDNGVLPLL TPMSEIAGRM AVQVGAHYLE KPYGGKGILL GGVPGVPPAD VVIIGAGTVG 190 200 210 220 230 240 TSAARVAMGM GAQVTIIDKN LDRLRYLDEL YGGRIKTLAS NQFNIEMSVR YADLLIGAVL 250 260 270 280 290 300 VVGAKAPKLV TVEMVKQMKQ GSVIVDVAVD QGGSIETVDR VTVHSDPVYE KYGVIHYAVD 310 320 330 340 350 360 NMPGAVARTS TFALTNATLP YALELANRGC PRAFTNRALA RGVNTYKGKL TCRAVGESLN 370 380 MECHDLGDVL RSDAALNFRQ KLQKRREDE

References

[1]	"The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota." Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K. Genome Res. 18:442-448(2008) [PubMed: 18218977] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009389 Genomic DNA. Translation: BAF58839.1.
RefSeq	YP_001211208.1. NC_009454.1.
3D structure databases
ProteinModelPortal	A5D4H9.
SMR	A5D4H9. Positions 1-371.
ModBase	Search...
Protein-protein interaction databases
STRING	A5D4H9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5138418.
GenomeReviews	Gene locus PTH_0658 in contig AP009389_GR.
KEGG	pth:PTH_0658.
PATRIC	22908248. VBIPelThe8413_0746.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0686.
HOGENOM	HBG289735.
OMA	AIGYETV.
Enzyme and pathway databases
BioCyc	PTHE370438:PTH_0658-MONOMER.
Family and domain databases
InterPro	IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5D4H9_PELTS

Accession

Primary (citable) accession number: A5D4H9

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)