A5D1S4 (A5D1S4_PELTS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	TrpC EMBL BAF59806.1
Synonyms:	trpC HAMAP MF_00134
Ordered Locus Names:	PTH_1625

Organism

Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) [Complete proteome] [HAMAP]

Taxonomic identifier

370438 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Pelotomaculum

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134 SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134 SAAS SAAS013798
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134 SAAS SAAS013798
Molecular function	Decarboxylase HAMAP MF_00134 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5D1S4 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: CB8DCCC9D57E6BCD	FASTA	259	27,992
	10 20 30 40 50 60 MINKIIACKK ADLAGQKKLL PVERLKELMT GNLPSRPLAS ALRRPGQVTI IAEVKRASPL 70 80 90 100 110 120 KGILNKNLDP LRMAQEYGEA GAAAISVLTE ERFFLGRPSD LVSVRSETAL PVLRKDFIID 130 140 150 160 170 180 PYQIFESRVL GADAVLLIAA VLQGGQLAEL KALADELGMS CLIEVHTEAE LYRSLSAGAE 190 200 210 220 230 240 IIGINNRDLG TFKTDLNKTL TLSKLIDGQK VTVVSESGIR SRNDIEMLKE CGVHAALVGE 250 ALVCRPDPGR ALKELKGCV

References

[1]	"The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota." Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K. Genome Res. 18:442-448(2008) [PubMed: 18218977] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009389 Genomic DNA. Translation: BAF59806.1.
RefSeq	YP_001212175.1. NC_009454.1.
3D structure databases
ProteinModelPortal	A5D1S4.
ModBase	Search...
Protein-protein interaction databases
STRING	A5D1S4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5140348.
GenomeReviews	Gene locus PTH_1625 in contig AP009389_GR.
KEGG	pth:PTH_1625.
PATRIC	22910491. VBIPelThe8413_1837.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0134.
HOGENOM	HBG540956.
OMA	LEYAVPH.
ProtClustDB	PRK00278.
Enzyme and pathway databases
BioCyc	PTHE370438:PTH_1625-MONOMER.
Family and domain databases
HAMAP	MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5D1S4_PELTS

Accession

Primary (citable) accession number: A5D1S4

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)