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A5D1D2 (A5D1D2_PELTS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphopantetheine adenylyltransferase 2 HAMAP MF_00151
EC=2.7.7.3 HAMAP MF_00151
Alternative name(s):
Dephospho-CoA pyrophosphorylase 2 HAMAP MF_00151
Pantetheine-phosphate adenylyltransferase 2 HAMAP MF_00151
Gene names
Name:CoaD EMBL BAF59944.1
Synonyms:coaD2 HAMAP MF_00151
Ordered Locus Names:PTH_1763
OrganismPelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) [Complete proteome] [HAMAP]
Taxonomic identifier370438 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Peptococcaceae › Pelotomaculum

Protein attributes

Sequence length167 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151

Catalytic activity

ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151

Subunit structure

Homohexamer By similarity. HAMAP MF_00151

Subcellular location

Cytoplasm By similarity HAMAP MF_00151.

Sequence similarities

Belongs to the bacterial CoaD family. HAMAP MF_00151

Sequences

Sequence LengthMass (Da)Tools
A5D1D2 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 48312FC80C01F55E

FASTA16718,669
        10         20         30         40         50         60 
MRTAICPGSF DPVTFGHLDI ISRASLLFDR VIAAVSRNPC KNPMFSVEER MEMLKSVLSP 

        70         80         90        100        110        120 
YPNVEVDSYE GLTVNYALQQ KARTIVRGLR VISDFENEFK MALVNKKLSC HVETIFLMTK 

       130        140        150        160 
AEYSFISSTV VKEVAFFGGS LASLVPPLVE KKVREKLKSL ERVSEGG

« Hide

References

[1]"The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota."
Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K.
Genome Res. 18:442-448(2008) [PubMed: 18218977] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009389 Genomic DNA. Translation: BAF59944.1.
RefSeqYP_001212313.1. NC_009454.1.

3D structure databases

ProteinModelPortalA5D1D2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5D1D2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5140018.
GenomeReviewsGene locus PTH_1763 in contig AP009389_GR.
KEGGpth:PTH_1763.
PATRIC22910781. VBIPelThe8413_1982.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0669.
HOGENOMHBG288308.
OMAMDHARER.
ProtClustDBCLSK2324506.

Enzyme and pathway databases

BioCycPTHE370438:PTH_1763-MONOMER.

Family and domain databases

HAMAPMF_00151. PPAT_bact.
[Tree]
InterProIPR004821. Cyt_trans-rel.
IPR004820. Cytidylyltransf.
IPR001980. LPS_biosynth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK00954.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
PRINTSPR01020. LPSBIOSNTHSS.
TIGRFAMsTIGR01510. CoaD_prev_kdtB. 1 hit.
TIGR00125. Cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5D1D2_PELTS
AccessionPrimary (citable) accession number: A5D1D2
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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