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A5CYN8

- PGK_PELTS

UniProt

A5CYN8 - PGK_PELTS

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Protein
Phosphoglycerate kinase
Gene
pgk, PTH_2722
Organism
Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei118 – 1181Substrate By similarity
Binding sitei151 – 1511Substrate By similarity
Binding sitei201 – 2011ATP By similarity
Binding sitei323 – 3231ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi349 – 3524ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPTHE370438:GCGQ-2777-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:PTH_2722
OrganismiPelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)
Taxonomic identifieri370438 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaePelotomaculum
ProteomesiUP000006556: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Phosphoglycerate kinaseUniRule annotation
PRO_1000076596Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi370438.PTH_2722.

Structurei

3D structure databases

ProteinModelPortaliA5CYN8.
SMRiA5CYN8. Positions 1-393.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5CYN8-1 [UniParc]FASTAAdd to Basket

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MAKKTVRDID VKGKRVLLRV DFNVPMENGR VADDVKIKEA VPTINYLIGQ    50
KARVILVSHL GRPKGRVDER YKMDPVARRL SELLGKTVVK AGDCVGEAAR 100
SAVAQMQDGD VVLLENVRFH PEEEKNDEKF ARQLAELADV FVNDAFGTAH 150
RAHASTEGVA GFLPAVAGLL MEKELEILGR LLTSPERPFA AVVGGSKVSD 200
KLGVIFNLLT KVDTVIIGGG MANTFLKAQG YSVGKSLLEA DKIDLARKLI 250
AEARSREVKL LLPVDVVVAP GPAPGQEQRT VPVDQIPAEW MALDIGPESI 300
RLFTEALRAA RTVVWNGPMG VFEMDPFARG TEAIARTLAE LNAVTVIGGG 350
DTAAAAKKAG VAGKMTHIST GGGASLEFLE GKQLPGVRAL LDK 393
Length:393
Mass (Da):42,064
Last modified:June 12, 2007 - v1
Checksum:i2E4C0DCE8A50D80D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP009389 Genomic DNA. Translation: BAF60903.1.
RefSeqiYP_001213272.1. NC_009454.1.

Genome annotation databases

EnsemblBacteriaiBAF60903; BAF60903; PTH_2722.
GeneIDi5138950.
KEGGipth:PTH_2722.
PATRICi22912929. VBIPelThe8413_3050.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP009389 Genomic DNA. Translation: BAF60903.1 .
RefSeqi YP_001213272.1. NC_009454.1.

3D structure databases

ProteinModelPortali A5CYN8.
SMRi A5CYN8. Positions 1-393.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 370438.PTH_2722.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAF60903 ; BAF60903 ; PTH_2722 .
GeneIDi 5138950.
KEGGi pth:PTH_2722.
PATRICi 22912929. VBIPelThe8413_3050.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci PTHE370438:GCGQ-2777-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota."
    Kosaka T., Kato S., Shimoyama T., Ishii S., Abe T., Watanabe K.
    Genome Res. 18:442-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13744 / JCM 10971 / SI.

Entry informationi

Entry nameiPGK_PELTS
AccessioniPrimary (citable) accession number: A5CYN8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 12, 2007
Last modified: June 11, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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