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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCVES412965:G1G2Q-87-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:COSY_0085
OrganismiVesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)
Taxonomic identifieri412965 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriasulfur-oxidizing symbionts
Proteomesi
  • UP000000247 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181431 – 572Arginine--tRNA ligaseAdd BLAST572

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi412965.COSY_0085

Structurei

3D structure databases

ProteinModelPortaliA5CXW2
SMRiA5CXW2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6202 hits
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A5CXW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQLLQQLLV QSLEVLMDNN ILESMPENIR VDHSKDKAQG DFASNIAMLL
60 70 80 90 100
SEQAQCSSKV LAQKIKANFP DSVDVEKIEI VGPGFINFFM SQSSNALVVE
110 120 130 140 150
DIIKQGGNYG LSNIGMGQRV LLEFVSANPT GPLHVGHGRG VAYGAAVAHL
160 170 180 190 200
LRAVGFEVDC EYYVNDAGRQ MDILAISVYL RYVETEQFPD NCYKGDYIFD
210 220 230 240 250
IAKKISGVKK LDIFTNTCKD TSEWKVQKNS IDKERYIDDL IANCKLQLGS
260 270 280 290 300
DYRKVFDFAI NSILSDIKID LADFGVEYHQ WFSEQSLVDS GLSEEIVKKL
310 320 330 340 350
QDLGYIYEKE GALWFRTTDF GDDLDRVVVR DNGIHTYFSY DIAYHLGKFE
360 370 380 390 400
RGYDRIINIW GADHHGYIAR VKASIKALNY NPDKLEILLV QFVNLFRDGK
410 420 430 440 450
KVSMSTRSGS FITLKELREE VGNDVVRFFY ILRKSTQHMD FNLDLAKSKS
460 470 480 490 500
NENPVFYIQY AYVRICSVLK QGMPFMADID LLVLNNELET LLIKELNRYK
510 520 530 540 550
DILQSSALNY EPHVLACYLR KLAGYFHSYY NNCEFLVDDD KLRNSRLLLI
560 570
TAVQQILANG LNLLGISTPN SM
Length:572
Mass (Da):65,124
Last modified:June 12, 2007 - v1
Checksum:i4900D5213CB3B058
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009247 Genomic DNA Translation: BAF61221.1
RefSeqiWP_011929491.1, NC_009465.1

Genome annotation databases

EnsemblBacteriaiBAF61221; BAF61221; COSY_0085
KEGGivok:COSY_0085

Similar proteinsi

Entry informationi

Entry nameiSYR_VESOH
AccessioniPrimary (citable) accession number: A5CXW2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: February 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome