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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (COSY_0073)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei113SubstrateUniRule annotation1
Binding sitei146SubstrateUniRule annotation1
Binding sitei197ATPUniRule annotation1
Binding sitei314ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi340 – 343ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCVES412965:G1G2Q-74-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:COSY_0072
OrganismiVesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA)
Taxonomic identifieri412965 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriasulfur-oxidizing symbionts
Proteomesi
  • UP000000247 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000580891 – 392Phosphoglycerate kinaseAdd BLAST392

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi412965.COSY_0072

Structurei

3D structure databases

ProteinModelPortaliA5CXU9
SMRiA5CXU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

A5CXU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVINLSDLD LNSKRVLIRQ DLNVPISNGV VTSDKRIKAS LPTIKMALNQ
60 70 80 90 100
GAKVMLMSHR GRPIEGDPSD GFSLQPVADR LSELLNTTVR LEKDWLDGVE
110 120 130 140 150
MNNGKVVLCE NVRFNVGEMV NDDELSKRMA AICDIFVMDA FGTAHRAQAS
160 170 180 190 200
TYGVAKYAPI ACSGPLLSEE LDALGKALDN PKRPMVAIVG GSKVSTKLTV
210 220 230 240 250
LESLSKIVDQ LVVGGGIANT FIAAQGFNVG KSLCEYDLIP IAKKLMEDCE
260 270 280 290 300
IPVSKDVVCG KEFSDVAEAE TKASKDVADD DMIFDIGPKS AQQLADIMRN
310 320 330 340 350
AGTIVWNGPV GVFEFDQFAG GTETLGKAIA ESNAFSIAGG GDTLAAVDKY
360 370 380 390
GIEDKISYIS TGGGAFLEFL EGKKLPAVEV LEQRALEVIK LA
Length:392
Mass (Da):41,878
Last modified:June 12, 2007 - v1
Checksum:i884A9F8876B2C3CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009247 Genomic DNA Translation: BAF61208.1
RefSeqiWP_011929478.1, NC_009465.1

Genome annotation databases

EnsemblBacteriaiBAF61208; BAF61208; COSY_0072
KEGGivok:COSY_0072

Similar proteinsi

Entry informationi

Entry nameiPGK_VESOH
AccessioniPrimary (citable) accession number: A5CXU9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 12, 2007
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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