A5CWK1 (A5CWK1_VESOH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribonuclease 3 HAMAP MF_00104
EC=3.1.26.3 HAMAP MF_00104

Alternative name(s):
Ribonuclease III HAMAP MF_00104

Gene names

Name:	rnc HAMAP MF_00104
Ordered Locus Names:	COSY_0566

Organism

Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) [Complete proteome] [HAMAP] EMBL BAF61683.1

Taxonomic identifier

412965 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › sulfur-oxidizing symbionts

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. HAMAP MF_00104
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104
Subcellular location	Cytoplasm By similarity HAMAP MF_00104.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. HAMAP MF_00104 Contains 1 RNase III domain. HAMAP MF_00104

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00104
Ligand	RNA-binding HAMAP MF_00104
Molecular function	Endonuclease HAMAP MF_00104 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA processing Inferred from electronic annotation. Source: HAMAP rRNA catabolic process Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	1 – 123	123	RNase III By similarity HAMAP MF_00104
	Domain	150 – 220	71	DRBM By similarity HAMAP MF_00104

Sequences

	Sequence		Length	Mass (Da)
	A5CWK1 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 53761BDAB39D05D1	FASTA	221	24,947
	10 20 30 40 50 60 MKKLQKKINY QFKDLSLLKL ALTHRSTGRN NNERLEFLGD SILGVAISKE LYQRFPCVDE 70 80 90 100 110 120 GKLSRLRSHL IRGQTLVQLG TALELSNNLI LGSGELKSGG YRRESIQADT VEAIFGAVLL 130 140 150 160 170 180 DSNFETTNMV ILGLFKVLLN SISPDDSLKD SKTQLQEYLQ KRGNILPKYK LIDTTGKDHN 190 200 210 220 AIFMVNCFLE DQKLQVKQSA KSIKKAEQFC AQILLKKLKK S

References

[1]

"Reduced genome of the thioautotrophic intracellular symbiont in a deep-sea clam, Calyptogena okutanii." Kuwahara H., Yoshida T., Takaki Y., Shimamura S., Nishi S., Harada M., Matsuyama K., Takishita K., Kawato M., Uematsu K., Fujiwara Y., Sato T., Kato C., Kitagawa M., Kato I., Maruyama T. Curr. Biol. 17:881-886(2007) [PubMed: 17493812] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009247 Genomic DNA. Translation: BAF61683.1.
RefSeq	YP_001219407.1. NC_009465.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5CWK1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5172471.
GenomeReviews	Gene locus COSY_0566 in contig AP009247_GR.
KEGG	vok:COSY_0566.
PATRIC	32020981. VBICanVes128383_0568.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0571.
HOGENOM	HBG744556.
OMA	ALTHKSF.
ProtClustDB	CLSK850637.
Family and domain databases
HAMAP	MF_00104. RNase_III. [Tree]
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
KO	K03685.
PANTHER	PTHR11207. PTHR11207. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
SUPFAM	SSF69065. RNase_III. 1 hit.
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5CWK1_VESOH

Accession

Primary (citable) accession number: A5CWK1

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)