Reviewed, UniProtKB/Swiss-Prot A5CV47 (DCD_CLAM3)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CMM_2900

Organism

Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP]

Taxonomic identifier

443906 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009708

Sequences

	Sequence		Length	Mass (Da)
	A5CV47-1 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: D7A6EA31CC38CB9B	FASTA	201	22,086
	10 20 30 40 50 60 MLLSDRDITA ELDAGRVALD PYDPGMLQPA SIDVRIDRFF RLFDNHKYPY IDPAEDQPEL 70 80 90 100 110 120 TRLIESKPGE PFILHPGEFV LGSTFELVTL PDDVAARLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFSGHVTLEL SNVATLPIKL WPGMKIGQLC FFRLSSPAKK PYGSGEYASR YQGQRGPTAS 190 200 RSHLNFVHTD VTVTDAGQQG E

References

[1]

"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity." Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D. J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM711867 Genomic DNA. Translation: CAN02986.1.
RefSeq	YP_001223645.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5CV47.
Genome annotation databases
GeneID	5174678.
GenomeReviews	Gene locus CMM_2900 in contig AM711867_GR.
KEGG	cmi:CMM_2900.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GSRYQGQ.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. DeoxyUTP_pyroPase_dom. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CLAM3

Accession

Primary (citable) accession number: A5CV47

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 12, 2007
Last modified:	November 3, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)