A5CU85 (A5CU85_CLAM3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
EC=1.1.1.17 HAMAP MF_00196

Gene names

Name:	mtlD HAMAP MF_00196 EMBL CAN02672.1
Ordered Locus Names:	CMM_2589

Organism

Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP] EMBL CAN02672.1

Taxonomic identifier

443906 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196 SAAS SAAS000669
Sequence similarities	Belongs to the mannitol dehydrogenase family. HAMAP MF_00196

Ontologies

Keywords
Ligand	NAD HAMAP MF_00196 SAAS SAAS000669
Molecular function	Oxidoreductase HAMAP MF_00196 SAAS SAAS023028 EMBL CAN02672.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro mannitol-1-phosphate 5-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	3 – 14	12	NAD By similarity HAMAP MF_00196

Sequences

	Sequence		Length	Mass (Da)
	A5CU85 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 2A15DC9E573616E2	FASTA	389	41,254
	10 20 30 40 50 60 MKAVHFGAGN IGRGFVGLIL HEAGYEVVFA DVNAELIGHL ASADSYRVTE VGPHARDWTV 70 80 90 100 110 120 TGFRAIDSAA DGEALIAEIA TADVVTTAVG PNILRFVAPA IAAGLRARSA DLGPVAVMAC 130 140 150 160 170 180 ENAINATDTL RDEIAKALGD ETDALGRAVF ANTAVDRIVP NQDPAAGLDV IVEDFSEWVV 190 200 210 220 230 240 ERTPFGDAVP EIAGATFVDD LAPYIERKLF TVNTGHATVA YHGYARGAVS QSDAMAIPEV 250 260 270 280 290 300 ADEVRQVLEE TSALLVAKHG LDEGEQAAYR EKNLARFANA ALADTVERVG RQPLRKLSRE 310 320 330 340 350 360 ERFVGPASQL AERGLPHDAL VRAMGQALRF DPAGDPQALE LQGLLATDTA ADLVRRVTGL 370 380 DDQHPLTPDL VAVVDAAQAD RRSAPRHRA

References

[1]

"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity." Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D. J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM711867 Genomic DNA. Translation: CAN02672.1.
RefSeq	YP_001223334.1. NC_009480.1.
3D structure databases
ProteinModelPortal	A5CU85.
ModBase	Search...
Protein-protein interaction databases
STRING	A5CU85.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5175980.
GenomeReviews	Gene locus CMM_2589 in contig AM711867_GR.
KEGG	cmi:CMM_2589.
PATRIC	21456021. VBIClaMic82482_2708.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0246.
HOGENOM	HBG568825.
OMA	FANTAVD.
ProtClustDB	PRK02318.
Family and domain databases
HAMAP	MF_00196. Mannitol_dehydrog. [Tree]
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR013328. DH_multihelical. IPR023028. Mannitol_1_phos_5_DH. IPR000669. Mannitol_DH. IPR013118. Mannitol_DH_C. IPR013131. Mannitol_DH_N. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00009.
Pfam	PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view]
PRINTS	PR00084. MTLDHDRGNASE.
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5CU85_CLAM3

Accession

Primary (citable) accession number: A5CU85

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)