A5CU74 (GLMM_CLAM3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	CMM_2578

Organism

Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP]

Taxonomic identifier

443906 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	437 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 437	437	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000068899
Sites
	Active site	93	1	Phosphoserine intermediate By similarity
	Metal binding	93	1	Magnesium; via phosphate group By similarity
	Metal binding	230	1	Magnesium By similarity
	Metal binding	232	1	Magnesium By similarity
	Metal binding	234	1	Magnesium By similarity
Amino acid modifications
	Modified residue	93	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5CU74 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: C5EFB5AFD02579D4	FASTA	437	45,704
	10 20 30 40 50 60 MPRLFGTDGV RGLANGETIT ADLALRLAQA AAHVLGQDAR DPRVSGEFIA AAVAAGLASS 70 80 90 100 110 120 GVDVFDAGVI PTPATAYLIA DFDADFGVMI SASHNPAPDN GIKFFAAGGR KLADELEDRI 130 140 150 160 170 180 EAQLSRPVLL PTGADVGRIR RFADAEDRYV LHLLGTLQHR LDGIHVVLDC AHGAAAGISP 190 200 210 220 230 240 EVFTDAGARV TVIGNDPDGM NINDRVGSTH LDLLAEAVLA HGADVGIAHD GDADRCLAVD 250 260 270 280 290 300 HTGAIIDGDQ IMAVLALSMA RRGLLAERTL VATVMSNLGL RIAMAENDIT VMQTRVGDRY 310 320 330 340 350 360 VLEAMNEGGY SLGGEQSGHL VIAEHATTGD GILTGIQLLG EMAATGKSLH ELASVMTVYP 370 380 390 400 410 420 QVMINVRGVD RDRVGDDAEL NAAVARAEAE LGDTGRILMR ASGTEPMIRV MVEAADQATA 430 ERHAEELAAL VTERLAI

References

[1]

"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity." Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D. J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCPPB 382.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM711867 Genomic DNA. Translation: CAN02661.1.
RefSeq	YP_001223323.1. NC_009480.1.
3D structure databases
ProteinModelPortal	A5CU74.
ModBase	Search...
Protein-protein interaction databases
STRING	A5CU74.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5174761.
GenomeReviews	Gene locus CMM_2578 in contig AM711867_GR.
KEGG	cmi:CMM_2578.
PATRIC	21455999. VBIClaMic82482_2697.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Enzyme and pathway databases
BioCyc	CMIC443906:CMM_2578-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CLAM3

Accession

Primary (citable) accession number: A5CU74

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program