A5CT40 (A5CT40_CLAM3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259 RuleBase RU003981
EC=2.1.2.10 HAMAP MF_00259 RuleBase RU003981

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259 EMBL CAN02267.1
Ordered Locus Names:	CMM_2197

Organism

Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP] EMBL CAN02267.1

Taxonomic identifier

443906 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903 Methyltransferase EMBL CAN02267.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5CT40 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: AF4B887D0947F457	FASTA	406	41,907
	10 20 30 40 50 60 MPDAPADTAP DAAAAAPPRR SPLHAVHEAA GASFTDFAGW LMPVRYTSDL AEHRAVREAA 70 80 90 100 110 120 GIFDISHMAE IAVEGEGAAA FLDSVLAGKL SAIAEWQAKY TLLLDPSGGI VDDLIVYRTG 130 140 150 160 170 180 EESFLVVANA GNHDPVLAVL AEAAAGRDDV EVDDASDDVA LIAVQGPVSR AILEATAGLE 190 200 210 220 230 240 TETPLEALRY YRATAARFAG QDVLVARTGY TGEDGYELYV ATEDAVALWE ALVAAGTPLG 250 260 270 280 290 300 LLNTGLACRD TLRLEAGMPL YGHELGLHTL PVQAGLGKVV ALGKEGDFRG RAAVEKGPGP 310 320 330 340 350 360 VARVLVGLVT EGRRAPRADY PVYAEEAAGD SAAALEAAME ATEGAVAPVG IITSGALSPT 370 380 390 400 LGHPVAMAYV DPSLAAPGTR LAVDVRGTRV PATVVTLPFY SRKALA

References

[1]

"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity." Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D. J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM711867 Genomic DNA. Translation: CAN02267.1.
RefSeq	YP_001222942.1. NC_009480.1.
3D structure databases
ProteinModelPortal	A5CT40.
ModBase	Search...
Protein-protein interaction databases
STRING	A5CT40.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5175751.
GenomeReviews	Gene locus CMM_2197 in contig AM711867_GR.
KEGG	cmi:CMM_2197.
PATRIC	21455237. VBIClaMic82482_2325.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HBG299834.
OMA	KALYGGM.
ProtClustDB	CLSK2325392.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5CT40_CLAM3

Accession

Primary (citable) accession number: A5CT40

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)