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A5CSL3 (DAPF_CLAM3) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7
Gene names
Name:dapF
Ordered Locus Names:CMM_2021
OrganismClavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP]
Taxonomic identifier443906 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292Diaminopimelate epimerase HAMAP MF_00197
PRO_1000011870

Sites

Active site871 By similarity
Active site2301 By similarity

Sequences

Sequence LengthMass (Da)Tools
A5CSL3 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: B4B7E00A7FB0EBDF

FASTA29230,578
        10         20         30         40         50         60 
MADLQFTKGQ GTGNDFVLFA DPAGEIDLTD TQVQALCDRH FGIGADGTIR AVLSTRIPEG 

        70         80         90        100        110        120 
RAALEEDPDA EWFMDYRNVD GSPAEMCGNG IRVFTLFLIE NGLIELPPGR TIPIGTRAGV 

       130        140        150        160        170        180 
RDVQRSGSGF QVDLGRWELA GGEPLVRAKD LQVARPGLGI DVGNPHVVVA LSSEDELAEA 

       190        200        210        220        230        240 
DLAFVPQLDP EPAAGANVEL VVPADPLVVD GVGHITMRVH ERGSGETLSC GTGAAAAALA 

       250        260        270        280        290 
TRHWAGAAAP HQWRVQLPGG ALGVRMFPTE DGEHVGLSGP AELVFDGVVA LA

« Hide

References

[1]"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity."
Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. expand/collapse author list , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D.
J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCPPB 382.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM711867 Genomic DNA. Translation: CAN02084.1.
RefSeqYP_001222763.1. NC_009480.1.

3D structure databases

ProteinModelPortalA5CSL3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5CSL3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5174176.
GenomeReviewsGene locus CMM_2021 in contig AM711867_GR.
KEGGcmi:CMM_2021.
PATRIC21454871. VBIClaMic82482_2141.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0253.
HOGENOMHBG399442.
OMAITLACGS.
ProtClustDBPRK00450.

Enzyme and pathway databases

BioCycCMIC443906:CMM_2021-MONOMER.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPF_CLAM3
AccessionPrimary (citable) accession number: A5CSL3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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