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A5CRZ1 (AROC_CLAM3) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:CMM_1798
OrganismClavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP]
Taxonomic identifier443906 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 412412Chorismate synthase HAMAP MF_00300
PRO_0000322397

Sequences

Sequence LengthMass (Da)Tools
A5CRZ1 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 3EE358540D81B85A

FASTA41242,970
        10         20         30         40         50         60 
MLRWLTAGES HGPELIAVLE GLPAGVPVSL DGIRADLARR KLGYGRGARM AFEQDELSLS 

        70         80         90        100        110        120 
TGVVHGRTLG SPIAVRIGNT EWPKWVDIMS PEPVDPEKLQ GARAAALTRP RPGHADLVGM 

       130        140        150        160        170        180 
QKYDFDEARP VLERASARET AARVALGAVA RAFLAELGIT LVSHTLSIGP VRVPEGAPLP 

       190        200        210        220        230        240 
TPADVDALDA DPLRCFHPET SARMVAEVDD TKSSGDTVGG VVEVLAYDLP PGLGSHVHWD 

       250        260        270        280        290        300 
RRLDSKLAAA LMGIQAIKGV EVGDGFLTTT RRGSEAHDEL FSTDAGIGRS TDRAGGTEGG 

       310        320        330        340        350        360 
MSTGTVLRVR AGMKPIATVP RALRTIDTAT GGAAPANHQR SDVCAVPAAG VVAEAMVALT 

       370        380        390        400        410 
LADAVLEKFG GDSVGETLRN LRGYLDAIPE GRRTGADLVD EADAAPPAAP EA

« Hide

References

[1]"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity."
Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. expand/collapse author list , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D.
J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCPPB 382.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM711867 Genomic DNA. Translation: CAN01854.1.
RefSeqYP_001222541.1. NC_009480.1.

3D structure databases

ProteinModelPortalA5CRZ1.
SMRA5CRZ1. Positions 1-390.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5CRZ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5175614.
GenomeReviewsGene locus CMM_1798 in contig AM711867_GR.
KEGGcmi:CMM_1798.
PATRIC21454409. VBIClaMic82482_1918.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMAMLRWLTA.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycCMIC443906:CMM_1798-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_CLAM3
AccessionPrimary (citable) accession number: A5CRZ1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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