A5CPE3 (MQO_CLAM3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	CMM_0904

Organism

Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP]

Taxonomic identifier

443906 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325492

Sequences

	Sequence		Length	Mass (Da)
	A5CPE3 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: C67007DAA5459171	FASTA	492	53,864
	10 20 30 40 50 60 MSESAEPVDV VLVGGGIMSA TLGTLIKQLE PDWTIQIFER LGEVAMESSN PWNNAGTGHA 70 80 90 100 110 120 ALCELNYTPE KDGKIEIGSA TRINEQFQLS RQFWAHLVTA GAVPEPKEFI NPTPHMTFVR 130 140 150 160 170 180 GKENAEFLRR RFDAMRAHPL FEAMEYSEDP AVIHSWAPLL VLQREKDEVI AATRFEGGTD 190 200 210 220 230 240 VDFGALTNKL IDYLTEHGAA LHLNHEVRGL SQNPDGSWHL RIRNDVGRST VQVDAKFVFI 250 260 270 280 290 300 GAGGGALPLL QKSGIPEIKG FGGFPISGEW FRTDDPEIVA RHRAKVYGKA AIGSPPMSVP 310 320 330 340 350 360 HLDTRVVGGE TSLLFGPYAG FSPRFLKKGS LLDLFASIRP HNIIPMLAVA KDNLSLIKYL 370 380 390 400 410 420 VSQLIASKEK KFDALREFMP TADPKDWYQV TAGQRVQVMK KDAKKGGVLQ FGTEVVAAAD 430 440 450 460 470 480 GSIAGLLGAS PGASTAVPIM LDVLERCFPD RIAGWKKPLT RMIPNYGTLV ASDPKKTPKI 490 IQETAEVLEL QH

References

[1]

"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity." Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D. J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCPPB 382.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM711867 Genomic DNA. Translation: CAN00941.1.
RefSeq	YP_001221644.1. NC_009480.1.
3D structure databases
ProteinModelPortal	A5CPE3.
ModBase	Search...
Protein-protein interaction databases
STRING	A5CPE3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5174621.
GenomeReviews	Gene locus CMM_0904 in contig AM711867_GR.
KEGG	cmi:CMM_0904.
PATRIC	21452537. VBIClaMic82482_0999.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	NTQFEVS.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	CMIC443906:CMM_0904-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_CLAM3

Accession

Primary (citable) accession number: A5CPE3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program