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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:CMM_0904
OrganismiClavibacter michiganensis subsp. michiganensis (strain NCPPB 382)
Taxonomic identifieri443906 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrobacteriaceaeClavibacter
Proteomesi
  • UP000001564 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003254921 – 492Probable malate:quinone oxidoreductaseAdd BLAST492

Interactioni

Protein-protein interaction databases

STRINGi443906.CMM_0904.

Structurei

3D structure databases

ProteinModelPortaliA5CPE3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR006231. MQO.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

A5CPE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESAEPVDV VLVGGGIMSA TLGTLIKQLE PDWTIQIFER LGEVAMESSN
60 70 80 90 100
PWNNAGTGHA ALCELNYTPE KDGKIEIGSA TRINEQFQLS RQFWAHLVTA
110 120 130 140 150
GAVPEPKEFI NPTPHMTFVR GKENAEFLRR RFDAMRAHPL FEAMEYSEDP
160 170 180 190 200
AVIHSWAPLL VLQREKDEVI AATRFEGGTD VDFGALTNKL IDYLTEHGAA
210 220 230 240 250
LHLNHEVRGL SQNPDGSWHL RIRNDVGRST VQVDAKFVFI GAGGGALPLL
260 270 280 290 300
QKSGIPEIKG FGGFPISGEW FRTDDPEIVA RHRAKVYGKA AIGSPPMSVP
310 320 330 340 350
HLDTRVVGGE TSLLFGPYAG FSPRFLKKGS LLDLFASIRP HNIIPMLAVA
360 370 380 390 400
KDNLSLIKYL VSQLIASKEK KFDALREFMP TADPKDWYQV TAGQRVQVMK
410 420 430 440 450
KDAKKGGVLQ FGTEVVAAAD GSIAGLLGAS PGASTAVPIM LDVLERCFPD
460 470 480 490
RIAGWKKPLT RMIPNYGTLV ASDPKKTPKI IQETAEVLEL QH
Length:492
Mass (Da):53,864
Last modified:June 12, 2007 - v1
Checksum:iC67007DAA5459171
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM711867 Genomic DNA. Translation: CAN00941.1.

Genome annotation databases

EnsemblBacteriaiCAN00941; CAN00941; CMM_0904.
KEGGicmi:CMM_0904.

Similar proteinsi

Entry informationi

Entry nameiMQO_CLAM3
AccessioniPrimary (citable) accession number: A5CPE3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 12, 2007
Last modified: October 25, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families