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Reviewed, UniProtKB/Swiss-Prot A5CPC1 (XYLA_CLAM3)

Last modified November 3, 2009. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: CMM_0882
OrganismClavibacter michiganensis subsp. michiganensis (strain NCPPB 382) [Complete proteome] [HAMAP]
Taxonomic identifier443906 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Microbacteriaceae › Clavibacter

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Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Xylose isomerase HAMAP MF_00455
PRO_1000026438

Sites

Active site541 By similarity
Active site571 By similarity
Metal binding1811Magnesium 1 By similarity
Metal binding2171Magnesium 1 By similarity
Metal binding2171Magnesium 2 By similarity
Metal binding2201Magnesium 2 By similarity
Metal binding2451Magnesium 1 By similarity
Metal binding2551Magnesium 2 By similarity
Metal binding2571Magnesium 2 By similarity
Metal binding2931Magnesium 1 By similarity

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Sequences

Sequence LengthMass (Da)Tools
A5CPC1-1 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 2841ADD244D09F38

FASTA39743,837
        10         20         30         40         50         60 
MALTPTREDK FSFGLWTIGY TGADPFGGPT RSDLDVVEGV ERISELGAYG LTFHDDDLFA 

        70         80         90        100        110        120 
FGSTDAERQT QIDRLKGALS DTGIVVPMVT TNLFSAPVFK DGGFTSNDRA VRRFAIRKVL 

       130        140        150        160        170        180 
RNIDLAAELG AQTFVMWGGR EGAEYDSAKD VRGALERYRE AVNLLGDYVT DKGYDIRFAI 

       190        200        210        220        230        240 
EPKPNEPRGD ILLPTLGHAL AFIETLERPE LVGVNPEVGH EQMAGLNFTA GIMQALYQGK 

       250        260        270        280        290        300 
LFHIDLNGQR GIKYDQDLVF GHGDLQNAFS LVDLLENGGV GGGRSYDGPR HFDYKPSRTE 

       310        320        330        340        350        360 
DITGVWDSAA ANMRMYLLLK ERAQAFRADP EVQEALAAAK VQEIYTPTLN EGESYDDILA 

       370        380        390 
DRSSYEDFDA PSYFDAKGFG FVRLNQLALE HLMGARS

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References

[1]"The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity."
Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M., Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O., Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C. expand/collapse author list , Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O., Bartels D.
J. Bacteriol. 190:2138-2149(2008) [PubMed: 18192381] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

AM711867 Genomic DNA. Translation: CAN00919.1.
RefSeqYP_001221622.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA5CPC1.

Genome annotation databases

GeneID5173138.
GenomeReviewsGene locus CMM_0882 in contig AM711867_GR.
KEGGcmi:CMM_0882.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATFHDDDL.

Family and domain databases

HAMAPMF_00455.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
IPR018115. Xylose_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02631. xylA_Arthro. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYLA_CLAM3
AccessionPrimary (citable) accession number: A5CPC1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: November 3, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents