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Protein

Xylose isomerase

Gene

xylA

Organism
Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei54UniRule annotation1
Active sitei57UniRule annotation1
Metal bindingi181Magnesium 1UniRule annotation1
Metal bindingi217Magnesium 1UniRule annotation1
Metal bindingi217Magnesium 2UniRule annotation1
Metal bindingi220Magnesium 2UniRule annotation1
Metal bindingi245Magnesium 1UniRule annotation1
Metal bindingi255Magnesium 2UniRule annotation1
Metal bindingi257Magnesium 2UniRule annotation1
Metal bindingi293Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:CMM_0882
OrganismiClavibacter michiganensis subsp. michiganensis (strain NCPPB 382)
Taxonomic identifieri443906 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrobacteriaceaeClavibacter
Proteomesi
  • UP000001564 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000264381 – 397Xylose isomeraseAdd BLAST397

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi443906.CMM_0882

Structurei

3D structure databases

ProteinModelPortaliA5CPC1
SMRiA5CPC1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000022596
KOiK01805
OMAiNQLAIEH

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013453 XylA_actinobac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02631 xylA_Arthro, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

A5CPC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTPTREDK FSFGLWTIGY TGADPFGGPT RSDLDVVEGV ERISELGAYG
60 70 80 90 100
LTFHDDDLFA FGSTDAERQT QIDRLKGALS DTGIVVPMVT TNLFSAPVFK
110 120 130 140 150
DGGFTSNDRA VRRFAIRKVL RNIDLAAELG AQTFVMWGGR EGAEYDSAKD
160 170 180 190 200
VRGALERYRE AVNLLGDYVT DKGYDIRFAI EPKPNEPRGD ILLPTLGHAL
210 220 230 240 250
AFIETLERPE LVGVNPEVGH EQMAGLNFTA GIMQALYQGK LFHIDLNGQR
260 270 280 290 300
GIKYDQDLVF GHGDLQNAFS LVDLLENGGV GGGRSYDGPR HFDYKPSRTE
310 320 330 340 350
DITGVWDSAA ANMRMYLLLK ERAQAFRADP EVQEALAAAK VQEIYTPTLN
360 370 380 390
EGESYDDILA DRSSYEDFDA PSYFDAKGFG FVRLNQLALE HLMGARS
Length:397
Mass (Da):43,837
Last modified:June 12, 2007 - v1
Checksum:i2841ADD244D09F38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM711867 Genomic DNA Translation: CAN00919.1
RefSeqiWP_012037567.1, NC_009480.1

Genome annotation databases

EnsemblBacteriaiCAN00919; CAN00919; CMM_0882
KEGGicmi:CMM_0882

Similar proteinsi

Entry informationi

Entry nameiXYLA_CLAM3
AccessioniPrimary (citable) accession number: A5CPC1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: April 25, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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