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A5CKE2 (A5CKE2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Platelet glycoprotein Ib alpha polypeptide EMBL CAM97225.1
Gene names
Name:GP1BA EMBL CAM97225.1
OrganismHomo sapiens (Human) EMBL CAM97225.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length639 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue6391 EMBL CAM97225.1

Sequences

Sequence LengthMass (Da)Tools
A5CKE2 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 387BFD59BE431A60

FASTA63970,248
        10         20         30         40         50         60 
MPLLLLLLLL PSPLHPHPIC EVSKVASHLE VNCDKRNLTA LPPDLPKDTT ILHLSENLLY 

        70         80         90        100        110        120 
TFSLATLMPY TRLTQLNLDR CELTKLQVDG TLPVLGTLDL SHNQLQSLPL LGQTLPALTV 

       130        140        150        160        170        180 
LDVSFNRLTS LPLGALRGLG ELQELYLKGN ELKTLPPGLL TPTPKLEKLS LANNNLTELP 

       190        200        210        220        230        240 
AGLLNGLENL DTLLLQENSL YTIPKGFFGS HLLPFAFLHG NPWLCNCEIL YFRRWLQDNA 

       250        260        270        280        290        300 
ENVYVWKQGV DVKAMTSNVA SVQCDNSDKF PVYKYPGKGC PTLGDEGDTD LYDYYPEEDT 

       310        320        330        340        350        360 
EGDKVRATRT VVKFPTKAHT TPWGLFYSWS TASLDSQMPS SLHPTQESTK EQTTFPPRWT 

       370        380        390        400        410        420 
PNFTLHMESI TFSKTPKSTT EPTPSPTTSE PVPEPAPNMT TLEPTPSPTT PEPTSEPAPS 

       430        440        450        460        470        480 
PTTPEPTSEP APSPTTPEPT PIPTIATSPT ILVSATSLIT PKSTFLTTTK PVSLLESTKK 

       490        500        510        520        530        540 
TIPELDQPPK LRGVLQGHLE SSRNDPFLHP DFCCLLPLGF YVLGLFWLLF ASVVLILLLS 

       550        560        570        580        590        600 
WVGHVKPQAL DSGQGAALTT ATQTTHLELQ RGRQVTVPRA WLLFLRGSLP TFRSSLFLWV 

       610        620        630 
RPNGRVGPLV AGRRPSALSQ GRGQDLLSTV SIRYSGHSL 

« Hide

References

[1]"An additional 39 bp repeat detected in the human platelet glycoprotein Ib alpha sequence."
Witter K.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 170743 EMBL CAM97225.1.
[2]"Single Novel Mutation in Transmembrane Region of Glycoprotein IX Affects Platelet Surface Expressions of Glycoprotein GP-Ib-IX Complex and Causes Bernard Soulier Syndrome."
Xu L., Peng B., Yu S., Liu L., Zhang D., Sun G., Wang P., Sun N., Hu Q., Li X., Cao F.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Novel Bernard-Soulier syndrome variants caused by compound heterozygous mutations (case I) or a cytoplasmic tail truncation (case II) of GPIb?"
Yamamoto N., Akamatsu N., Sakuraba H., Matsuno K., Hosoya R., Nogami H., Kasahara K., Mitsuyama S., Arai M.
Thromb. Res. 131:e160-e167(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GU133003 Genomic DNA. Translation: ACY72565.1.
AB576655 Genomic DNA. Translation: BAJ15421.1.
AM709890 Genomic DNA. Translation: CAM97225.1.
UniGeneHs.1472.

3D structure databases

ProteinModelPortalA5CKE2.
SMRA5CKE2. Positions 17-300.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEA5CKE2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOGENOMHOG000234361.
HOVERGENHBG051790.
PhylomeDBA5CKE2.

Gene expression databases

ArrayExpressA5CKE2.

Family and domain databases

InterProIPR000483. Cys-rich_flank_reg_C.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR000372. LRR-contain_N.
[Graphical view]
PfamPF00560. LRR_1. 1 hit.
PF01462. LRRNT. 1 hit.
[Graphical view]
SMARTSM00369. LRR_TYP. 2 hits.
SM00082. LRRCT. 1 hit.
SM00013. LRRNT. 1 hit.
[Graphical view]
PROSITEPS51450. LRR. 6 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio27032107.
PMAP-CutDBA5CKE2.

Entry information

Entry nameA5CKE2_HUMAN
AccessionPrimary (citable) accession number: A5CKE2
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.