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Protein
Submitted name:

Platelet glycoprotein Ib alpha

Gene

GP1BA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Platelet glycoprotein Ib alphaImported
Submitted name:
Platelet glycoprotein Ib alpha polypeptideImported
Gene namesi
Name:GP1BAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei518 – 542HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500763526917 – 639Sequence analysisAdd BLAST623

Proteomic databases

PeptideAtlasiA5CKE2.
PRIDEiA5CKE2.

Expressioni

Gene expression databases

BgeeiENSG00000185245.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000329380.

Structurei

3D structure databases

ProteinModelPortaliA5CKE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 51LRRNTInterPro annotationAdd BLAST33
Domaini221 – 281LRRCTInterPro annotationAdd BLAST61

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000234361.
HOVERGENiHBG051790.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR000372. LRRNT.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF01462. LRRNT. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 5 hits.
SM00082. LRRCT. 1 hit.
SM00013. LRRNT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A5CKE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLLLLLLLL PSPLHPHPIC EVSKVASHLE VNCDKRNLTA LPPDLPKDTT
60 70 80 90 100
ILHLSENLLY TFSLATLMPY TRLTQLNLDR CELTKLQVDG TLPVLGTLDL
110 120 130 140 150
SHNQLQSLPL LGQTLPALTV LDVSFNRLTS LPLGALRGLG ELQELYLKGN
160 170 180 190 200
ELKTLPPGLL TPTPKLEKLS LANNNLTELP AGLLNGLENL DTLLLQENSL
210 220 230 240 250
YTIPKGFFGS HLLPFAFLHG NPWLCNCEIL YFRRWLQDNA ENVYVWKQGV
260 270 280 290 300
DVKAMTSNVA SVQCDNSDKF PVYKYPGKGC PTLGDEGDTD LYDYYPEEDT
310 320 330 340 350
EGDKVRATRT VVKFPTKAHT TPWGLFYSWS TASLDSQMPS SLHPTQESTK
360 370 380 390 400
EQTTFPPRWT PNFTLHMESI TFSKTPKSTT EPTPSPTTSE PVPEPAPNMT
410 420 430 440 450
TLEPTPSPTT PEPTSEPAPS PTTPEPTSEP APSPTTPEPT PIPTIATSPT
460 470 480 490 500
ILVSATSLIT PKSTFLTTTK PVSLLESTKK TIPELDQPPK LRGVLQGHLE
510 520 530 540 550
SSRNDPFLHP DFCCLLPLGF YVLGLFWLLF ASVVLILLLS WVGHVKPQAL
560 570 580 590 600
DSGQGAALTT ATQTTHLELQ RGRQVTVPRA WLLFLRGSLP TFRSSLFLWV
610 620 630
RPNGRVGPLV AGRRPSALSQ GRGQDLLSTV SIRYSGHSL
Length:639
Mass (Da):70,248
Last modified:June 12, 2007 - v1
Checksum:i387BFD59BE431A60
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei639Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU133003 Genomic DNA. Translation: ACY72565.1.
AB576655 Genomic DNA. Translation: BAJ15421.1.
AM709890 Genomic DNA. Translation: CAM97225.1.
UniGeneiHs.1472.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU133003 Genomic DNA. Translation: ACY72565.1.
AB576655 Genomic DNA. Translation: BAJ15421.1.
AM709890 Genomic DNA. Translation: CAM97225.1.
UniGeneiHs.1472.

3D structure databases

ProteinModelPortaliA5CKE2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000329380.

Proteomic databases

PeptideAtlasiA5CKE2.
PRIDEiA5CKE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000234361.
HOVERGENiHBG051790.

Gene expression databases

BgeeiENSG00000185245.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR000372. LRRNT.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF01462. LRRNT. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 5 hits.
SM00082. LRRCT. 1 hit.
SM00013. LRRNT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA5CKE2_HUMAN
AccessioniPrimary (citable) accession number: A5CKE2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: November 2, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.