A5CFM2 (A5CFM2_ORITB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pseudouridine synthase RuleBase RU003886
EC=5.4.99.- RuleBase RU003886

Gene names

Name:	rluC EMBL CAM81239.1
Ordered Locus Names:	OTBS_2144 EMBL CAM81239.1

Organism

Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi) [Complete proteome] [HAMAP] EMBL CAM81239.1

Taxonomic identifier

357244 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Orientia › Orientia tsutsugamushi

Protein attributes

Sequence length	312 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the pseudouridine synthase rluA family. RuleBase RU004243 Contains 1 S4 RNA-binding domain. SAAS SAAS006145

Ontologies

Keywords
Ligand	RNA-binding SAAS SAAS006145
Molecular function	Isomerase SAAS SAAS006145 RuleBase RU003886 Lyase EMBL CAM81239.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pseudouridine synthesis Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW lyase activity Inferred from electronic annotation. Source: UniProtKB-KW pseudouridine synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5CFM2 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: BE2DC437956860ED	FASTA	312	35,285
	10 20 30 40 50 60 MKITISNCLV TTRLDKFLKR KYSHLTQGVI ERGIRKGHIK VNDAKSKAKL QVKDNDILTI 70 80 90 100 110 120 ADYLTSCSNQ KHIKLKKKVK DNVGVKALAH KIVNNYKIAE TSDYIIINKP ALLPTQGGSK 130 140 150 160 170 180 ISLSLDDAIK YLNKSFYYDF KLVHRLDRET TGLLIIAKNH GTAIKLSQAF LHHSIEKEYI 190 200 210 220 230 240 AILQGVPSQL SGEIITNITK TGDRMIETQN GGKVSITKYQ VKAISINSQL SLVSFIPVTG 250 260 270 280 290 300 RTHQLRVHAA KIGYPIIGDK KYNISNTYYN YSLKLHAAKI CIPKHLFGNQ RIYYAPLPYQ 310 FQQVISTFFD HN

References

[1]

"The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes." Cho N.H., Kim H.R., Lee J.H., Kim S.Y., Kim J., Cha S., Kim S.Y., Darby A.C., Fuxelius H.H., Yin J., Kim J.H., Kim J., Lee S.J., Koh Y.S., Jang W.J., Park K.H., Andersson S.G.E., Choi M.S., Kim I.S. Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Boryong EMBL CAM81239.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM494475 Genomic DNA. Translation: CAM81239.1.
RefSeq	YP_001249240.1. NC_009488.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	357244.OTBS_2144.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAM81239; CAM81239; OTBS_2144.
GeneID	5219186.
KEGG	ots:OTBS_2144.
PATRIC	22825859. VBIOriTsu83812_2334.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0564.
HOGENOM	HOG000275914.
KO	K06179.
OMA	DINDNNG.
ProtClustDB	CLSK2517043.
Family and domain databases
Gene3D	3.10.290.10. 1 hit.
InterPro	IPR020103. PsdUridine_synth_cat_dom. IPR006224. PsdUridine_synth_RluC/D_CS. IPR006145. PsdUridine_synth_RsuA/RluD. IPR002942. S4_RNA-bd. [Graphical view]
Pfam	PF00849. PseudoU_synth_2. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
SUPFAM	SSF55120. PsdUridine_synth_cat_dom. 1 hit.
PROSITE	PS01129. PSI_RLU. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5CFM2_ORITB

Accession

Primary (citable) accession number: A5CFM2

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)