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A5CFM2

- A5CFM2_ORITB

UniProt

A5CFM2 - A5CFM2_ORITB

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Protein
Pseudouridine synthase
Gene
rluC, OTBS_2144
Organism
Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
  2. lyase activity Source: UniProtKB-KW
  3. pseudouridine synthase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations, LyaseImported

Keywords - Ligandi

RNA-bindingSAAS annotations

Enzyme and pathway databases

BioCyciOTSU357244:GCA5-2180-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pseudouridine synthaseUniRule annotation (EC:5.4.99.-UniRule annotation)
Gene namesi
Name:rluCImported
Ordered Locus Names:OTBS_2144Imported
OrganismiOrientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi)Imported
Taxonomic identifieri357244 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeOrientia
ProteomesiUP000001565: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi357244.OTBS_2144.

Structurei

3D structure databases

ProteinModelPortaliA5CFM2.

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase rluA family.UniRule annotation
Contains S4 RNA-binding domain.SAAS annotations
Contains SRNA-binding domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275914.
KOiK06179.
OMAiEAPMDEQ.
OrthoDBiEOG6P070X.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5CFM2-1 [UniParc]FASTAAdd to Basket

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MKITISNCLV TTRLDKFLKR KYSHLTQGVI ERGIRKGHIK VNDAKSKAKL    50
QVKDNDILTI ADYLTSCSNQ KHIKLKKKVK DNVGVKALAH KIVNNYKIAE 100
TSDYIIINKP ALLPTQGGSK ISLSLDDAIK YLNKSFYYDF KLVHRLDRET 150
TGLLIIAKNH GTAIKLSQAF LHHSIEKEYI AILQGVPSQL SGEIITNITK 200
TGDRMIETQN GGKVSITKYQ VKAISINSQL SLVSFIPVTG RTHQLRVHAA 250
KIGYPIIGDK KYNISNTYYN YSLKLHAAKI CIPKHLFGNQ RIYYAPLPYQ 300
FQQVISTFFD HN 312
Length:312
Mass (Da):35,285
Last modified:June 12, 2007 - v1
Checksum:iBE2DC437956860ED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM494475 Genomic DNA. Translation: CAM81239.1.
RefSeqiYP_001249240.1. NC_009488.1.

Genome annotation databases

EnsemblBacteriaiCAM81239; CAM81239; OTBS_2144.
GeneIDi5219186.
KEGGiots:OTBS_2144.
PATRICi22825859. VBIOriTsu83812_2334.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM494475 Genomic DNA. Translation: CAM81239.1 .
RefSeqi YP_001249240.1. NC_009488.1.

3D structure databases

ProteinModelPortali A5CFM2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 357244.OTBS_2144.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAM81239 ; CAM81239 ; OTBS_2144 .
GeneIDi 5219186.
KEGGi ots:OTBS_2144.
PATRICi 22825859. VBIOriTsu83812_2334.

Phylogenomic databases

eggNOGi COG0564.
HOGENOMi HOG000275914.
KOi K06179.
OMAi EAPMDEQ.
OrthoDBi EOG6P070X.

Enzyme and pathway databases

BioCyci OTSU357244:GCA5-2180-MONOMER.

Family and domain databases

Gene3Di 3.10.290.10. 1 hit.
InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view ]
Pfami PF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view ]
SMARTi SM00363. S4. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
PROSITEi PS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes."
    Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y., Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J., Koh Y.-S., Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S., Kim I.-S.
    Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BoryongImported.

Entry informationi

Entry nameiA5CFM2_ORITB
AccessioniPrimary (citable) accession number: A5CFM2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: June 11, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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