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A5CF57

- FENR_ORITB

UniProt

A5CF57 - FENR_ORITB

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Protein

Ferredoxin--NADP reductase

Gene
OTBS_1841
Organism
Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.UniRule annotation

Cofactori

Binds 1 FAD per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381FAD By similarity
Binding sitei46 – 461FAD By similarity
Binding sitei51 – 511FAD By similarity
Binding sitei91 – 911FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei125 – 1251FAD; via amide nitrogen By similarity
Binding sitei291 – 2911FAD By similarity
Binding sitei331 – 3311FAD By similarity

GO - Molecular functioni

  1. ferredoxin-NADP+ reductase activity Source: UniProtKB-HAMAP
  2. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP
  3. NADP binding Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein, NADP

Enzyme and pathway databases

BioCyciOTSU357244:GCA5-1873-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin--NADP reductase (EC:1.18.1.2)
Short name:
FNR
Short name:
Fd-NADP(+) reductase
Gene namesi
Ordered Locus Names:OTBS_1841
OrganismiOrientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi)
Taxonomic identifieri357244 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeOrientia
ProteomesiUP000001565: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 338338Ferredoxin--NADP reductaseUniRule annotationPRO_0000364891Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi357244.OTBS_1841.

Structurei

3D structure databases

ProteinModelPortaliA5CF57.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0492.
HOGENOMiHOG000072909.
KOiK00384.
OMAiLFQVFQL.
OrthoDBiEOG661H9M.

Family and domain databases

HAMAPiMF_01685. FENR2.
InterProiIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSiPR00368. FADPNR.
PR00469. PNDRDTASEII.

Sequencei

Sequence statusi: Complete.

A5CF57-1 [UniParc]FASTAAdd to Basket

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MLSKNVHTAD VVIVGAGPVG LFAVFQAGML EMKCHVVDAL DCIGGQCVTL    50
YPDKPIYDIP AYPVITAAKL IEQLKQQVAP FDTVYHLGQQ VIGCKIDNDI 100
ITITTSAEQV ICSKSLIIAA GCGAFKYKRL ILDNIEAFEN KTVFYSVKDK 150
NKFINKKVVI AGGGDSAIDW TLLLSDVAEV IYLVHRRENF RCAPHSLNQI 200
KQLAEYGKVQ MIVPYQLAKL TGENGLLQEV LVTNFNGGTQ TLPADYLLAF 250
FGLAADLGPI HKWGLKTDLR RIEVNSITYE TTIPGIYAIG DVASYPGKLK 300
LILTGFAEAA TAMSHCYQRV FGKKMHFQYS TVKGVLRS 338
Length:338
Mass (Da):37,098
Last modified:June 12, 2007 - v1
Checksum:i28661CED9F045B3E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM494475 Genomic DNA. Translation: CAM80936.1.
RefSeqiWP_011945073.1. NC_009488.1.
YP_001249091.1. NC_009488.1.

Genome annotation databases

EnsemblBacteriaiCAM80936; CAM80936; OTBS_1841.
GeneIDi5218223.
KEGGiots:OTBS_1841.
PATRICi22825158. VBIOriTsu83812_1988.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM494475 Genomic DNA. Translation: CAM80936.1 .
RefSeqi WP_011945073.1. NC_009488.1.
YP_001249091.1. NC_009488.1.

3D structure databases

ProteinModelPortali A5CF57.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 357244.OTBS_1841.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAM80936 ; CAM80936 ; OTBS_1841 .
GeneIDi 5218223.
KEGGi ots:OTBS_1841.
PATRICi 22825158. VBIOriTsu83812_1988.

Phylogenomic databases

eggNOGi COG0492.
HOGENOMi HOG000072909.
KOi K00384.
OMAi LFQVFQL.
OrthoDBi EOG661H9M.

Enzyme and pathway databases

BioCyci OTSU357244:GCA5-1873-MONOMER.

Family and domain databases

HAMAPi MF_01685. FENR2.
InterProi IPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view ]
Pfami PF07992. Pyr_redox_2. 1 hit.
[Graphical view ]
PRINTSi PR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNeti Search...

Publicationsi

  1. "The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes."
    Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y., Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J., Koh Y.-S., Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S., Kim I.-S.
    Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Boryong.

Entry informationi

Entry nameiFENR_ORITB
AccessioniPrimary (citable) accession number: A5CF57
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: June 12, 2007
Last modified: September 3, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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