A5CCS2 (A5CCS2_ORITB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase assembly protein CtaG HAMAP MF_00155

Gene names

Name:	cox11 EMBL CAM79515.1
Synonyms:	ctaG HAMAP MF_00155
Ordered Locus Names:	OTBS_0449

Organism

Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi) [Complete proteome] [HAMAP]

Taxonomic identifier

357244 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Orientia

Protein attributes

Sequence length	175 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity. HAMAP MF_00155
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side By similarity HAMAP MF_00155.
Sequence similarities	Belongs to the COX11/CtaG family. HAMAP MF_00155

Ontologies

Keywords
Cellular component	Cell inner membrane HAMAP MF_00155 Cell membrane Membrane
Domain	Signal-anchor HAMAP MF_00155 Transmembrane Transmembrane helix HAMAP MF_00155
Ligand	Copper HAMAP MF_00155
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	respiratory chain complex IV assembly Inferred from electronic annotation. Source: HAMAP
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Topological domain	1 – 3	3	Cytoplasmic By similarity HAMAP MF_00155
	Transmembrane	4 – 26	23	Helical; Signal-anchor for type II membrane protein; By similarity HAMAP MF_00155
	Topological domain	27 – 175	149	Periplasmic By similarity HAMAP MF_00155

Sequences

	Sequence		Length	Mass (Da)
	A5CCS2 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 382862AE5A7019C0	FASTA	175	20,205
	10 20 30 40 50 60 MKAKNNEIIF TLISLIVSML ILSFASVPIY SLFCKVTGFG GTVRQQIVSS KKKGKKQITI 70 80 90 100 110 120 NFDANIEQNL QWQFIPKQKS ITVTTGENNL VFYYSRNLTN RDIVGTAIYN VTPNKAGKYF 130 140 150 160 170 VKIYCFCFEE QLLKKQEEIL MPVSFYIDPA IEDDPYMNDV NTITLSYTFF KIREQ

References

[1]

"The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes." Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y., Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J., Koh Y.-S., Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S., Kim I.-S. Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007) [PubMed: 17483455] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM494475 Genomic DNA. Translation: CAM79515.1.
RefSeq	YP_001248355.1. NC_009488.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5CCS2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5218781.
GenomeReviews	Gene locus OTBS_0449 in contig AM494475_GR.
KEGG	ots:OTBS_0449.
PATRIC	22822104. VBIOriTsu83812_0479.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3175.
HOGENOM	HBG525908.
OMA	KLIFYRA.
ProtClustDB	PRK05089.
Enzyme and pathway databases
BioCyc	OTSU357244:OTBS_0449-MONOMER.
Family and domain databases
HAMAP	MF_00155. CtaG. [Tree]
InterPro	IPR023471. CtaG/Cox11_dom. IPR007533. Cyt_c_oxidase_assmbl_CtaG. [Graphical view]
Gene3D	G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.
KO	K02258.
PANTHER	PTHR21320. CtaG_Cox11. 1 hit.
Pfam	PF04442. CtaG_Cox11. 1 hit. [Graphical view]
PIRSF	PIRSF005413. COX11. 1 hit.
SUPFAM	SSF110111. CtaG_Cox11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5CCS2_ORITB

Accession

Primary (citable) accession number: A5CCS2

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)