A5CCI5 (A5CCI5_ORITB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase EMBL CAM79415.1
EC=2.3.1.37 EMBL CAM79415.1

Gene names

Name:	hemA EMBL CAM79415.1
Ordered Locus Names:	OTBS_0349

Organism

Orientia tsutsugamushi (strain Boryong) (Rickettsia tsutsugamushi) [Complete proteome] [HAMAP]

Taxonomic identifier

357244 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Orientia

Protein attributes

Sequence length	403 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Acyltransferase EMBL CAM79415.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5CCI5 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 68E3354DD22F8F01	FASTA	403	44,469
	10 20 30 40 50 60 MLSYNNFFDN HLHSIKLEGR YRKFTCIKKS TKWFPYNICA QTGKKVLIWC TNDYLGMSFH 70 80 90 100 110 120 PEVLSSAVLA VKQMGVGSGG TRNIGGNNSA IVELEELLAI LHKKQKALVF TSGYVANDTT 130 140 150 160 170 180 LQTLAKIIPG LVFISDEYNH ASIIAGIRNS RAEKHIYFHN NMQSLQQILS SIPINQPKII 190 200 210 220 230 240 VFEAIYSMSG TIAAVKEICN LAKMYNALTY IDEVHSVGLY GDDGSGICTL TGLFNQVDII 250 260 270 280 290 300 QGNLAKAYGA IGGYIAANSN IIDAIRSTAS GFIFTTALPP VISCAAMTSI KYLMKSNKER 310 320 330 340 350 360 LKLQETVAKL KDSLTSAGIR YLTNNSHIIA IVIGEPVLTQ RVAQILLEEY NIYIQAINFP 370 380 390 400 TVPRGTERLR ITPTPFHTDG MIHNLTVALK QILLNLNIYA ALR

References

[1]

"The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes." Cho N.-H., Kim H.-R., Lee J.-H., Kim S.-Y., Kim J., Cha S., Kim S.-Y., Darby A.C., Fuxelius H.-H., Yin J., Kim J.H., Kim J., Lee S.J., Koh Y.-S., Jang W.-J., Park K.-H., Andersson S.G.E., Choi M.-S., Kim I.-S. Proc. Natl. Acad. Sci. U.S.A. 104:7981-7986(2007) [PubMed: 17483455] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM494475 Genomic DNA. Translation: CAM79415.1.
RefSeq	YP_001248277.1. NC_009488.1.
3D structure databases
ProteinModelPortal	A5CCI5.
ModBase	Search...
Protein-protein interaction databases
STRING	A5CCI5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5218677.
GenomeReviews	Gene locus OTBS_0349 in contig AM494475_GR.
KEGG	ots:OTBS_0349.
PATRIC	22821892. VBIOriTsu83812_0377.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0156.
HOGENOM	HBG649839.
OMA	HLKESNE.
ProtClustDB	PRK09064.
Enzyme and pathway databases
BioCyc	OTSU357244:OTBS_0349-MONOMER.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5CCI5_ORITB

Accession

Primary (citable) accession number: A5CCI5

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)