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A5BBI6

- A5BBI6_VITVI

UniProt

A5BBI6 - A5BBI6_VITVI

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Protein

Malate dehydrogenase

Gene

VITISV_004210

Organism
Vitis vinifera (Grape)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotation

GO - Molecular functioni

  1. L-malate dehydrogenase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. malate metabolic process Source: InterPro
  3. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
Gene namesi
ORF Names:VITISV_004210Imported
OrganismiVitis vinifera (Grape)Imported
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

PTM / Processingi

Proteomic databases

PRIDEiA5BBI6.

Expressioni

Gene expression databases

ExpressionAtlasiA5BBI6. differential.

Interactioni

Protein-protein interaction databases

STRINGi29760.GSVIVG00027787001.

Structurei

3D structure databases

ProteinModelPortaliA5BBI6.
SMRiA5BBI6. Positions 39-347.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LDH/MDH superfamily. MDH type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0039.
HOGENOMiHOG000213792.
KOiK00026.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProiIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11540. PTHR11540. 1 hit.
PfamiPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMiSSF56327. SSF56327. 1 hit.
TIGRFAMsiTIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEiPS00068. MDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5BBI6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKASMAMRSV RSALRSGSSS SPSHFLRRCY CSESVPERKV TILGAAGGIG
60 70 80 90 100
QPLALLMKIN PLVSNLALYD IAGTPGVAAD VSHVNTISQV AGFMGEDQLG
110 120 130 140 150
KALEGSDVVI IPAGVPRKPG MTRDDLFNIN AGIVKSLCIA IAKYCPNALV
160 170 180 190 200
NVISNPVNST VPIAAEVFKK AGTFDEKKLF GVTTLDVVRA KTFYAAKAKV
210 220 230 240 250
PVSEVNVPVV GGHAGITILP LFSQTTPKSN NLSDEDIQAL TKRTQDGGTE
260 270 280 290 300
VVEAKAGKGS ATLSMAYAGA IFADACLKGL NGVPEVVECS YVQSSITELP
310 320 330 340 350
FFSSKVRLGK NGVEEVLGLG PLSDYEKEGL EKLKPDLKAS IEKGIKFAAQ

S
Length:351
Mass (Da):36,788
Last modified:June 12, 2007 - v1
Checksum:iECDFD001A6ABCFAC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM453488 Genomic DNA. Translation: CAN83064.1.
RefSeqiXP_002285356.1. XM_002285320.2.
UniGeneiVvi.1249.

Genome annotation databases

GeneIDi100253724.
KEGGivvi:100253724.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM453488 Genomic DNA. Translation: CAN83064.1 .
RefSeqi XP_002285356.1. XM_002285320.2.
UniGenei Vvi.1249.

3D structure databases

ProteinModelPortali A5BBI6.
SMRi A5BBI6. Positions 39-347.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 29760.GSVIVG00027787001.

Proteomic databases

PRIDEi A5BBI6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100253724.
KEGGi vvi:100253724.

Phylogenomic databases

eggNOGi COG0039.
HOGENOMi HOG000213792.
KOi K00026.

Gene expression databases

ExpressionAtlasi A5BBI6. differential.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProi IPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR11540. PTHR11540. 1 hit.
Pfami PF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMi SSF56327. SSF56327. 1 hit.
TIGRFAMsi TIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEi PS00068. MDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis vinifera L.): coping with a highly heterozygous genome."
    Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D., Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D., Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.
    , Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N., Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A., Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T., Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A., Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J., Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P., Gutin A., Van de Peer Y., Salamini F., Viola R.
    PLoS ONE 2:e1326-e1326(2007)
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA5BBI6_VITVI
AccessioniPrimary (citable) accession number: A5BBI6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)