A5BBI6 (A5BBI6_VITVI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malate dehydrogenase RuleBase RU003405
EC=1.1.1.37 RuleBase RU003405

Gene names

ORF Names:

VITISV_004210 EMBL CAN83064.1

Organism

Vitis vinifera (Grape) EMBL CAN83064.1

Taxonomic identifier

29760 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › rosids incertae sedis › Vitales › Vitaceae › Vitis

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	(S)-malate + NAD+ = oxaloacetate + NADH. RuleBase RU003405
Sequence similarities	Belongs to the LDH/MDH superfamily. MDH type 1 family. RuleBase RU004065

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle RuleBase RU003405
Ligand	NAD RuleBase RU003405
Molecular function	Oxidoreductase RuleBase RU003405
Gene Ontology (GO)
Biological_process	cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro malate metabolic process Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	L-malate dehydrogenase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5BBI6 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: ECDFD001A6ABCFAC	FASTA	351	36,788
	10 20 30 40 50 60 MKASMAMRSV RSALRSGSSS SPSHFLRRCY CSESVPERKV TILGAAGGIG QPLALLMKIN 70 80 90 100 110 120 PLVSNLALYD IAGTPGVAAD VSHVNTISQV AGFMGEDQLG KALEGSDVVI IPAGVPRKPG 130 140 150 160 170 180 MTRDDLFNIN AGIVKSLCIA IAKYCPNALV NVISNPVNST VPIAAEVFKK AGTFDEKKLF 190 200 210 220 230 240 GVTTLDVVRA KTFYAAKAKV PVSEVNVPVV GGHAGITILP LFSQTTPKSN NLSDEDIQAL 250 260 270 280 290 300 TKRTQDGGTE VVEAKAGKGS ATLSMAYAGA IFADACLKGL NGVPEVVECS YVQSSITELP 310 320 330 340 350 FFSSKVRLGK NGVEEVLGLG PLSDYEKEGL EKLKPDLKAS IEKGIKFAAQ S

References

[1]

"The first genome sequence of an elite grapevine cultivar (Pinot noir Vitis vinifera L.): coping with a highly heterozygous genome." Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D., Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D., Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T. , Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N., Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A., Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T., Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A., Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J., Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P., Gutin A., Van de Peer Y., Salamini F., Viola R. PLoS ONE 2:e1326-e1326(2007) Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM453488 Genomic DNA. Translation: CAN83064.1.
RefSeq	XP_002285356.1. XM_002285320.2.
UniGene	Vvi.1249.
3D structure databases
ProteinModelPortal	A5BBI6.
SMR	A5BBI6. Positions 39-347.
ModBase	Search...
Protein-protein interaction databases
STRING	29760.GSVIVG00027787001. A5BBI6.
Proteomic databases
PRIDE	A5BBI6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	100253724.
KEGG	vvi:100253724.
Phylogenomic databases
eggNOG	COG0039.
HOGENOM	HOG000213792.
KO	K00026.
ProtClustDB	PLN00106.
Gene expression databases
ArrayExpress	A5BBI6.
Family and domain databases
Gene3D	3.40.50.720. 1 hit. 3.90.110.10. 1 hit.
InterPro	IPR001557. L-lactate/malate_DH. IPR022383. Lactate/malate_DH_C. IPR001236. Lactate/malate_DH_N. IPR015955. Lactate_DH/Glyco_Ohase_4_C. IPR001252. Malate_DH_AS. IPR010097. Malate_DH_type1. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR11540. PTHR11540. 1 hit. PTHR11540:SF1. PTHR11540:SF1. 1 hit.
Pfam	PF02866. Ldh_1_C. 1 hit. PF00056. Ldh_1_N. 1 hit. [Graphical view]
PIRSF	PIRSF000102. Lac_mal_DH. 1 hit.
SUPFAM	SSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
TIGRFAMs	TIGR01772. MDH_euk_gproteo. 1 hit.
PROSITE	PS00068. MDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5BBI6_VITVI

Accession

Primary (citable) accession number: A5BBI6

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)