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Protein

Malate dehydrogenase

Gene

VITISV_004210

Organism
Vitis vinifera (Grape)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei123SubstrateUniRule annotation1
Binding sitei155SubstrateUniRule annotation1
Binding sitei189SubstrateUniRule annotation1
Active sitei213Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processTricarboxylic acid cycleUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
Gene namesi
ORF Names:VITISV_004210Imported
OrganismiVitis vinifera (Grape)Imported
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

Expressioni

Gene expression databases

ExpressionAtlasiA5BBI6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA5BBI6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 181Ldh_1_NInterPro annotationAdd BLAST143
Domaini183 – 347Ldh_1_CInterPro annotationAdd BLAST165

Sequence similaritiesi

Belongs to the LDH/MDH superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1494 Eukaryota
COG0039 LUCA
HOGENOMiHOG000213792
KOiK00026

Family and domain databases

Gene3Di3.90.110.10, 1 hit
InterProiView protein in InterPro
IPR001557 L-lactate/malate_DH
IPR022383 Lactate/malate_DH_C
IPR001236 Lactate/malate_DH_N
IPR015955 Lactate_DH/Glyco_Ohase_4_C
IPR001252 Malate_DH_AS
IPR010097 Malate_DH_type1
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF02866 Ldh_1_C, 1 hit
PF00056 Ldh_1_N, 1 hit
PIRSFiPIRSF000102 Lac_mal_DH, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
SSF56327 SSF56327, 1 hit
TIGRFAMsiTIGR01772 MDH_euk_gproteo, 1 hit
PROSITEiView protein in PROSITE
PS00068 MDH, 1 hit

Sequencei

Sequence statusi: Complete.

A5BBI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKASMAMRSV RSALRSGSSS SPSHFLRRCY CSESVPERKV TILGAAGGIG
60 70 80 90 100
QPLALLMKIN PLVSNLALYD IAGTPGVAAD VSHVNTISQV AGFMGEDQLG
110 120 130 140 150
KALEGSDVVI IPAGVPRKPG MTRDDLFNIN AGIVKSLCIA IAKYCPNALV
160 170 180 190 200
NVISNPVNST VPIAAEVFKK AGTFDEKKLF GVTTLDVVRA KTFYAAKAKV
210 220 230 240 250
PVSEVNVPVV GGHAGITILP LFSQTTPKSN NLSDEDIQAL TKRTQDGGTE
260 270 280 290 300
VVEAKAGKGS ATLSMAYAGA IFADACLKGL NGVPEVVECS YVQSSITELP
310 320 330 340 350
FFSSKVRLGK NGVEEVLGLG PLSDYEKEGL EKLKPDLKAS IEKGIKFAAQ

S
Length:351
Mass (Da):36,788
Last modified:June 12, 2007 - v1
Checksum:iECDFD001A6ABCFAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM453488 Genomic DNA Translation: CAN83064.1
RefSeqiXP_002285356.1, XM_002285320.4
UniGeneiVvi.1249

Genome annotation databases

EnsemblPlantsiVIT_19s0014g01640.t01; VIT_19s0014g01640.t01; VIT_19s0014g01640
GeneIDi100253724
GrameneiVIT_19s0014g01640.t01; VIT_19s0014g01640.t01; VIT_19s0014g01640
KEGGivvi:100253724

Similar proteinsi

Entry informationi

Entry nameiA5BBI6_VITVI
AccessioniPrimary (citable) accession number: A5BBI6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: May 23, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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