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Protein

Malate dehydrogenase

Gene

VITISV_004210

Organism
Vitis vinifera (Grape)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei213Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processTricarboxylic acid cycleUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
Gene namesi
ORF Names:VITISV_004210Imported
OrganismiVitis vinifera (Grape)Imported
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

PTM / Processingi

Proteomic databases

PRIDEiA5BBI6.

Structurei

3D structure databases

ProteinModelPortaliA5BBI6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 181Ldh_1_NInterPro annotationAdd BLAST143
Domaini183 – 347Ldh_1_CInterPro annotationAdd BLAST165

Sequence similaritiesi

Belongs to the LDH/MDH superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1494. Eukaryota.
COG0039. LUCA.
HOGENOMiHOG000213792.
KOiK00026.

Family and domain databases

Gene3Di3.90.110.10. 1 hit.
InterProiView protein in InterPro
IPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF56327. SSF56327. 1 hit.
TIGRFAMsiTIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEiView protein in PROSITE
PS00068. MDH. 1 hit.

Sequencei

Sequence statusi: Complete.

A5BBI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKASMAMRSV RSALRSGSSS SPSHFLRRCY CSESVPERKV TILGAAGGIG
60 70 80 90 100
QPLALLMKIN PLVSNLALYD IAGTPGVAAD VSHVNTISQV AGFMGEDQLG
110 120 130 140 150
KALEGSDVVI IPAGVPRKPG MTRDDLFNIN AGIVKSLCIA IAKYCPNALV
160 170 180 190 200
NVISNPVNST VPIAAEVFKK AGTFDEKKLF GVTTLDVVRA KTFYAAKAKV
210 220 230 240 250
PVSEVNVPVV GGHAGITILP LFSQTTPKSN NLSDEDIQAL TKRTQDGGTE
260 270 280 290 300
VVEAKAGKGS ATLSMAYAGA IFADACLKGL NGVPEVVECS YVQSSITELP
310 320 330 340 350
FFSSKVRLGK NGVEEVLGLG PLSDYEKEGL EKLKPDLKAS IEKGIKFAAQ

S
Length:351
Mass (Da):36,788
Last modified:June 12, 2007 - v1
Checksum:iECDFD001A6ABCFAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM453488 Genomic DNA. Translation: CAN83064.1.
RefSeqiXP_002285356.1. XM_002285320.4.
UniGeneiVvi.1249.

Genome annotation databases

GeneIDi100253724.
KEGGivvi:100253724.

Similar proteinsi

Entry informationi

Entry nameiA5BBI6_VITVI
AccessioniPrimary (citable) accession number: A5BBI6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: October 25, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)