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A5ABF5 (BGLM_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase M

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase M
Cellobiase M
Gentiobiase M
Gene names
Name:bglM
ORF Names:An11g00200
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length765 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 765746Probable beta-glucosidase M
PRO_5000242398

Sites

Active site2861 By similarity

Amino acid modifications

Glycosylation241N-linked (GlcNAc...) Potential
Glycosylation711N-linked (GlcNAc...) Potential
Glycosylation931N-linked (GlcNAc...) Potential
Glycosylation1261N-linked (GlcNAc...) Potential
Glycosylation2581N-linked (GlcNAc...) Potential
Glycosylation3141N-linked (GlcNAc...) Potential
Glycosylation3211N-linked (GlcNAc...) Potential
Glycosylation4321N-linked (GlcNAc...) Potential
Glycosylation5191N-linked (GlcNAc...) Potential
Glycosylation5411N-linked (GlcNAc...) Potential
Glycosylation6471N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A5ABF5 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 4D423F77A47A34A1

FASTA76582,116
        10         20         30         40         50         60 
MHSISALLSL LGGLALSSAA PTQNITSDAY FYGQSPAVYP SPEGTGTGSW ASAYEKAKAF 

        70         80         90        100        110        120 
VAQLTDDEKV NLTAGVSSKT GCSGFIAEIP RLNFTGLCVS DASNGLRGTD YVNGWSSGIH 

       130        140        150        160        170        180 
VGASWNRTLA RDRAKYMGQE FHRKGVNLLL GPVVGPLGRV AEGGRNWEGF SNDPYLTGAL 

       190        200        210        220        230        240 
VYETVQGVQS SGVGVSTKHY IGNEQETNRN PETVNGVDVA SVSSNIDDKT IHELYLWPFQ 

       250        260        270        280        290        300 
DAVLAGSVAI MCSYERINNS YACQNSKTLN GLLKTELGFQ GYVITDWGAQ HGGIASANAG 

       310        320        330        340        350        360 
LDMVMPETTL WGSNLTTAIA NGTMEASRLD DMATRIIATW YQLNQDTDFP TPGVGMPASA 

       370        380        390        400        410        420 
QSEHQVVVGT APDEKSTLLE SAIEGHVLVK NTNNALPLQT PQLVSVFGYD AKVTDSFDLA 

       430        440        450        460        470        480 
STVLGTSPLF QNYTLWVGGG SGSNSPAYVI APLNAIQQQA YEDGTSVLWD VSAQDPEVDP 

       490        500        510        520        530        540 
TSEACLVFIN SFATEGYDRS ALTDDYSDTL VTNVASKCNN TIVVVHNAGI RLVYNWIDHE 

       550        560        570        580        590        600 
NVTAVVLAHL PGQDTGHALV DILYGRANPS GKLPYTIAKQ ASDYGSLLHP SEPQTPYGLF 

       610        620        630        640        650        660 
PQSDFSEGVY IDYRAFDKDN ITPQFEFGFG LSYTTFAYSG LSIEKTNETT SEYPPSAAIQ 

       670        680        690        700        710        720 
EGGNPRLWDD LVTVTAEVQN SGSVDGAEVA QLYVGIPNGP VRQLRGFDKV LLSAGETAQV 

       730        740        750        760 
SFSLNRRDLS TWNVEAQQWQ LQSGTYQVYV GRSSRDLPLT GEFSI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM270218 Genomic DNA. Translation: CAK48253.1.
RefSeqXP_001394024.1. XM_001393987.1.

3D structure databases

ProteinModelPortalA5ABF5.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00008353; CADANGAP00008206; CADANGAG00008353.
GeneID4984238.
KEGGang:ANI_1_24094.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
KOK05349.
OrthoDBEOG7HMS8F.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetSearch...

Entry information

Entry nameBGLM_ASPNC
AccessionPrimary (citable) accession number: A5ABF5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 12, 2007
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries