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Protein

Translationally-controlled tumor protein

Gene

TPT1

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein
Short name:
TCTP
Gene namesi
Name:TPT1
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componentsi: Chromosome 13, Chromosome 5

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002952851 – 172Translationally-controlled tumor proteinAdd BLAST172

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei46Phosphoserine; by PLK1By similarity1
Modified residuei53PhosphoserineBy similarity1
Modified residuei64Phosphoserine; by PLK1By similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiA5A6K2
PRIDEiA5A6K2

Expressioni

Gene expression databases

BgeeiENSPTRG00000033724

Interactioni

Subunit structurei

Interacts with STEAP3.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000061081

Structurei

3D structure databases

ProteinModelPortaliA5A6K2
SMRiA5A6K2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 172TCTPPROSITE-ProRule annotationAdd BLAST172

Sequence similaritiesi

Belongs to the TCTP family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1727 Eukaryota
ENOG4111FVP LUCA
GeneTreeiENSGT00390000006051
HOGENOMiHOG000203361
HOVERGENiHBG002282
InParanoidiA5A6K2
OMAiFKDFEFY
OrthoDBiEOG091G0OTA
TreeFamiTF300238

Family and domain databases

Gene3Di2.170.150.10, 1 hit
InterProiView protein in InterPro
IPR011057 Mss4-like_sf
IPR011323 Mss4/transl-control_tumour
IPR034737 TCTP
IPR018103 Translation_control_tumour_CS
IPR018105 Translational_control_tumour_p
PANTHERiPTHR11991 PTHR11991, 1 hit
PfamiView protein in Pfam
PF00838 TCTP, 1 hit
PRINTSiPR01653 TCTPROTEIN
SUPFAMiSSF51316 SSF51316, 1 hit
PROSITEiView protein in PROSITE
PS01002 TCTP_1, 1 hit
PS01003 TCTP_2, 1 hit
PS51797 TCTP_3, 1 hit

Sequencei

Sequence statusi: Complete.

A5A6K2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYRDLISH DEMFSDIYKI REIADGLCLE VEGKMVSRTE GNIDDSLIGG
60 70 80 90 100
NASAEGPEGE GTESTVITGV DIVMNHHLQE TSFTKEAYKK YIKDYMKSIK
110 120 130 140 150
GKLEEQRPER VKPFMTGAAE QIKHILANFK NYQFFIGENM NPDGMVALLD
160 170
YREDGVTPYM IFFKDGLEME KC
Length:172
Mass (Da):19,595
Last modified:June 12, 2007 - v1
Checksum:iBD31399B71CA62F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB222130 mRNA Translation: BAF62375.1
RefSeqiNP_001092016.1, NM_001098546.2
XP_016776922.1, XM_016921433.1
UniGeneiPtr.6558

Genome annotation databases

EnsembliENSPTRT00000031134; ENSPTRP00000060060; ENSPTRG00000034210
ENSPTRT00000095548; ENSPTRP00000091361; ENSPTRG00000042843
GeneIDi452575
KEGGiptr:452575

Similar proteinsi

Entry informationi

Entry nameiTCTP_PANTR
AccessioniPrimary (citable) accession number: A5A6K2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: June 12, 2007
Last modified: June 20, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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