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Protein
Submitted name:

Motilin receptor

Gene

MLNR

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Motilin receptorImported
Gene namesi
Name:MLNRImported
OrganismiOryctolagus cuniculus (Rabbit)
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 63HelicalSequence analysisAdd BLAST23
Transmembranei75 – 93HelicalSequence analysisAdd BLAST19
Transmembranei113 – 134HelicalSequence analysisAdd BLAST22
Transmembranei155 – 177HelicalSequence analysisAdd BLAST23
Transmembranei235 – 258HelicalSequence analysisAdd BLAST24
Transmembranei287 – 310HelicalSequence analysisAdd BLAST24
Transmembranei322 – 346HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL5306.

Interactioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000012668.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 343G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST289

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00700000104070.
HOGENOMiHOG000272571.
HOVERGENiHBG006538.
KOiK05266.
OMAiRMMYFSQ.
OrthoDBiEOG091G09KB.
TreeFamiTF336314.

Family and domain databases

InterProiView protein in InterPro
IPR003905. GHS-R.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR01417. GHSRECEPTOR.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A5A4K8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSPWNGSDG PEDAREPPWA ALPPCDERRC SPFPLGTLVP VTAVCLGLFA
60 70 80 90 100
VGVSGNVVTV LLIGRYRDMR TTTNLYLGSM AVSDLLILLG LPFDLYRLWR
110 120 130 140 150
SRPWVFGQLL CRLSLYVGEG CTYASLLHMT ALSVERYLAI CRPLRARVLV
160 170 180 190 200
TRRRVRALIA ALWAVALLSA GPFFFLVGVE QDPAVFAAPD RNGTVPLDPS
210 220 230 240 250
SPAPASPPSG PGAEAAALFS RECRPSRAQL GLLRVMLWVT TAYFFLPFLC
260 270 280 290 300
LSILYGLIAR QLWRGRGPLR GPAATGRERG HRQTVRVLLV VVLAFIVCWL
310 320 330 340 350
PFHVGRIIYI NTQDSRMMYF SQYFNIVALQ LFYLSASINP ILYNLISKKY
360 370 380 390 400
RAAARRLLRE SRAGPSGVCG SRGPEQDVAG DTGGDTAGCT ETSANTKTAA
Length:400
Mass (Da):43,753
Last modified:May 29, 2007 - v1
Checksum:i203C09023473CBA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF526304 mRNA. Translation: ABP88928.1.
RefSeqiNP_001093437.1. NM_001099967.1.
UniGeneiOcu.7152.

Genome annotation databases

EnsembliENSOCUT00000014732; ENSOCUP00000012668; ENSOCUG00000014737.
GeneIDi100101581.
KEGGiocu:100101581.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF526304 mRNA. Translation: ABP88928.1.
RefSeqiNP_001093437.1. NM_001099967.1.
UniGeneiOcu.7152.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000012668.

Chemistry databases

ChEMBLiCHEMBL5306.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000014732; ENSOCUP00000012668; ENSOCUG00000014737.
GeneIDi100101581.
KEGGiocu:100101581.

Organism-specific databases

CTDi2862.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00700000104070.
HOGENOMiHOG000272571.
HOVERGENiHBG006538.
KOiK05266.
OMAiRMMYFSQ.
OrthoDBiEOG091G09KB.
TreeFamiTF336314.

Family and domain databases

InterProiView protein in InterPro
IPR003905. GHS-R.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR01417. GHSRECEPTOR.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA5A4K8_RABIT
AccessioniPrimary (citable) accession number: A5A4K8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 7, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.